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A granular leukocyte having cytoplasmic granules that stain with acid dyes and a nucleus with two lobes connected by a thin thread of chromatin.



a cell of vertebrates, including man, whose cytoplasm contains rounded granular structures that are stained by acid dyes, in particular by eosin. The eosinophils of the blood originate and mature in the bone marrow. They comprise 3–4 percent of leukocytes in the peripheral blood of a healthy human being. This level is subject to a daily rhythm and is regulated by the system which includes the pituitary body and the adrenal cortex.

In allergic reactions, eosinophils release the inhibitor histamine, which belongs to the prostaglandins E1 and E2. They also serve as phagocytes.

An increase in the percentage of eosinophils in the peripheral blood or an increase in their absolute number is called eosinophilia. As a rule, this condition is reactive in character, regardless of the degree of its severity. The possibility of developing eosinophilic leukemia is still a matter of dispute. Eosinophilia is accompanied by various reactions and diseases, predominantly allergic, including those related to the breaking down of the body’s resistance by parasites or medicinal and food allergens. Aggregations of eosinophils observed in the tissues, as, for example, in the mucosa of the bronchi (and sputum) in bronchial asthma, are called tissue eosinophilia. Eosinophilic infiltrates, large aggregations of eosinophils in the tissues, are occasionally observed in various organs, predominantly the lungs. They may run their course as short-term reactions or result in such severe illnesses as pneumonia, myocarditis, vasculitis, and meningoencephalitis. A number of other diseases are also accompanied by a high eosinophilia. In some cases it is impossible to establish the nature of the disease that is accompanied by a high eosinophilia. The condition may be observed even in people who are otherwise healthy.

Hürtle cells, one of the types of cells of the anterior lobe of the pituitary body, are also called eosinophils.


References in periodicals archive ?
Chehade's project entitled "Impact of Proton Pump Inhibitors on the Esophageal Transcriptome in Eosinophilic Esophagitis Subtypes" will receive funding of $70,000 per year for two years (a total of $140,000).
This is an important day for severe, eosinophilic asthma patients who have had limited treatment options for far too long, with many relying on oral steroids to manage their symptoms," noted Eugene Bleecker, professor and codirector of genetics, genomics and precision medicine at the University of Arizona Health Sciences.
cantonensis DNA by qPCR of CSF samples from 4 (11%) of 35 patients with eosinophilic meningitis confirms the parasite's presence in Laos.
Macroscopic biopsies showed an important eosinophilic infiltrate of the chorion and submucosa typical of eosinophilic cystitis (Fig.
The pre-specified primary analysis included hierarchical evaluation of these endpoints in the overall population, in patients with 150 eosinophilic cells/microliter or greater, and in patients with 300 eosinophilic cells/microliter or greater.
sup][1] Eosinophilic morphology of TSC-associated RCCs is reported in 48–61% of cases and described as chromophobe, granular-eosinophilic, or hybrid oncocytic tumors.
Multisystemic eosinophilic epitheliotropic disease is an extremely rare equine disease that affects several organ systems.
4 It has a prodromal allergic/atopic phase consisting of asthma and rhino sinusitis, an eosinophilic phase involving eosinophilic infiltration of various tissues and a vasculitic phase causing multi system involvement.
The biopsies showed eosinophilic cystitis and no sign of malignancy (Figure 3).
Conclusion: Eosinophilic cholecystitis in our population is mostly calculous which is very significant finding contrary to data given in western literature, where most of eosinophilic cholecystitis is aclculous.
Keywords: Bee polen, eosinophilic gastroenteropathy, good allergy
Patients with EG may present at any age, and any portion of the gastrointestinal tract, from the oesophagus to the colon, may be involved, [12] with symptoms varying according to the site of significant eosinophilic inflammation.

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