is most often a single bony lesion in very young patients, often less than 5 years old.
However the youngest reported case of isolated solitary orbital eosinophilic granuloma
was a 16month-old male patient from Iowa .
Patients with eosinophilic granuloma
develop solitary osteolytic lesions without systemic manifestations.
Decreased tobacco glycoprotein-induced lymphocyte proliferation in vitro in pulmonary eosinophilic granuloma
. Am J Respir Crit Care Med.
Also known as traumatic granuloma, eosinophilic granuloma
, and Riga-Fede disease, this lesion is usually caused by some sort of mechanical injury.
Other causes of the lumps included cephalhematoma deformans, eosinophilic granuloma
, or occult meningoceles or encephaloceles.
Microbiology revealed no organisms, but histological investigation suggested an eosinophilic granuloma
with dense eosinophilic infiltrates, histiocytes and scanty multinucleated giant cells.
For example, lichenoid dermatoses, sterile granulomatous disease, neoplasia and eosinophilic granuloma
complex all show similar signs.
Some areas may look raised, with a distinct border, as is seen with eosinophilic granuloma
. Cancers often have rough edges, are obvious "growths" that occupy space, and may emit a foul odor.
Previously classified into three different clinical entities including eosinophilic granuloma
, Hand-Schuller-Christian disease, and Letterer-Siwe disease, the current classification of LCH is made according to dissemination of the disease: single-system and multisystem LCH [2, 5].
Neoplasms associated with pulmonary eosinophilic granuloma
. Arch Pathol Lab Med.