In conclusion, epidurally administered levobupivacaine significantly delays the recovery index and complete recovery of neuromuscular function from vecuronium-induced block.
Epidurally administered mepivacaine delays recovery of train-of-four ratio from vecuronium-induced neuromuscular block.
The epidurally administered steroids are typically formulated as slow-release preparations, with maximum and prolonged local anti-inflammatory actions but reduced systemic effects.
Although the lack of pain relief in this case may suggest inefficiency of the epidurally administered etanercept in reducing radicular inflammation, it is likely that other factors are involved.
Clonidine, when used epidurally
or systemically, produces centrally mediated hypotension at low to moderate doses.
Cicek et al (12) have investigated the effects of different doses of epidural midazolam on spinal somatosensory evoked potentials (SSEP) and have found that epidurally
administered midazolam up to 150 [micro]g/kg caused no change in SSEP records, while 250 and 500 [micro]g/kg doses led to decreases.