epimer


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epimer

[′ep·ə·mər]
(organic chemistry)
A type of isomer in which the difference between the two compounds is the relative position of the H (hydrogen) group and OH (hydroxyl) group on the last asymmetric C (carbon) atom of the chain, as in the sugarsD-glucose andD-mannose.
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References in periodicals archive ?
2002) and using the chemical shift difference of the diastereomeric protons at C-26 (Agrawal 2005) revealed that compound 1 was a 7:3 mixture of the 25R and 25S epimers.
The analysis of the postadministration urine samples resulted in the qualitative detection of 11 compounds in the human excretion urines and 9 compounds in the chimeric mouse [epimethendiol (V) and the epimer of VII, present in human urines, were not found in the chimeric mouse], whereas in the nonchimeric mouse urine only 3 compounds were found [the parent drug methandienone (I), 6[beta]-hydroxymethandienone (II), and 1 additional isomer of VII (VIIa)].
A subgroup of very young children has a significant circulating concentration of the C-3 epimer of 25-hydroxy Vitamin D [Abstract].
25-0H Vitamin D is a challenging analyte to accurately measure in human blood due to the presence of 25-0H Vitamin D2, Vitamin D binding proteins, 25-0H Vitamin D metabolites such as 24, 25 (OH)2 Vitamin D, and C-3 epimers of 25-0H Vitamin D.
For newborns presenting with incomplete masculinization, this approach is not informative, since excretion of the THF and THB epimers (derived from cortisol and corticosterone, respectively) is negligible.
Misleading measures in vitamin D analysis: a novel LC-MS/MS assay to account for epimers and isobars.
Stereoselective total synthesis of (+)-oploxyne A, (--)-oploxyne B, and their C-10 epimers and structure revision of natural oploxyne B.
Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin- triggered epimers.
65, while their epimers (eichlerianic acid, ocotillone, and ocotillol) show this signal as a triplet at [[delta].
The epimers (+)-catechin and (-)-epicatechin exhibited negligible affinities for both CB1 and CB2.
Stability of tea polyphenol (-)-epigallocatechin-3-gallate and formation of dimers and epimers under common experimental conditions.