The ability of the Accucore Vanquish C18+ column to separate the two budesonide epimers
was further optimized by investigating the effect of separation temperature on peak resolution.
We analyze 10 different metabolites of vitamin D to look at the whole picture after separating the epimers
and isobars which are giving false positives.
7 min, and the two epimers
4 and 5 appeared as one sharp peak at 28.
Misleading measures in vitamin D analysis: a novel LCMS/ MS assay to account for epimers
Distinguishing between vascular plant sterols and sterols derived from marine phytoplankton is a complex task because of the lack of resolution between the C-24 epimers
of campesterol, [beta]-sitosterol and stigmasterol with the analytical techniques used.
For analytical purposes, the four diastereomers of 1 were separated in two pairs of epimers
(1a and 1b) by column chromatography through silica gel.
Some scientists found that aldonic acid could be converted in parts into its epimers
by heating a solution of the acid with pyridine or quinoline.
Resolvins, docosatrienes and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers
Aspirin's mechanism of action also involves the triggering of novel carbon 15 epimers
of LX or 15-epi-LX that mimic the bioactions of native LX.
However, the alkaloids ergosine, ergonine, ergine, and their epimers
were detected in low amounts, while ergovaline and its epimer
ergovalinine were the major components (about 80% of total) of the ergopeptine fraction, in agreement with Siegel and Bush (1997).
65, while their epimers
(eichlerianic acid, ocotillone, and ocotillol) show this signal as a triplet at [[delta].
25-0H Vitamin D is a challenging analyte to accurately measure in human blood due to the presence of 25-0H Vitamin D2, Vitamin D binding proteins, 25-0H Vitamin D metabolites such as 24, 25 (OH)2 Vitamin D, and C-3 epimers
of 25-0H Vitamin D.