The ability of the Accucore Vanquish C18+ column to separate the two budesonide
epimers was further optimized by investigating the effect of separation temperature on peak resolution.
We analyze 10 different metabolites of vitamin D to look at the whole picture after separating the
epimers and isobars which are giving false positives.
7 min, and the two
epimers 4 and 5 appeared as one sharp peak at 28.
Misleading measures in vitamin D analysis: a novel LCMS/ MS assay to account for
epimers and isobars.
Distinguishing between vascular plant sterols and sterols derived from marine phytoplankton is a complex task because of the lack of resolution between the C-24
epimers of campesterol, [beta]-sitosterol and stigmasterol with the analytical techniques used.
For analytical purposes, the four diastereomers of 1 were separated in two pairs of
epimers (1a and 1b) by column chromatography through silica gel.
Some scientists found that aldonic acid could be converted in parts into its
epimers by heating a solution of the acid with pyridine or quinoline.
Resolvins, docosatrienes and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered
epimers.
Aspirin's mechanism of action also involves the triggering of novel carbon 15
epimers of LX or 15-epi-LX that mimic the bioactions of native LX.
However, the alkaloids ergosine, ergonine, ergine, and their
epimers were detected in low amounts, while ergovaline and its
epimer ergovalinine were the major components (about 80% of total) of the ergopeptine fraction, in agreement with Siegel and Bush (1997).
65, while their
epimers (eichlerianic acid, ocotillone, and ocotillol) show this signal as a triplet at [[delta].
25-0H Vitamin D is a challenging analyte to accurately measure in human blood due to the presence of 25-0H Vitamin D2, Vitamin D binding proteins, 25-0H Vitamin D metabolites such as 24, 25 (OH)2 Vitamin D, and C-3
epimers of 25-0H Vitamin D.
