The major clinical finding was statistically significant improvement in episodic
memory function with neflamapimod, as assessed by immediate recall (p=0.
The researchers determined that 898 study group members (72%) fell into the never/sporadic use group, 141 (11%) were episodic
users, and 200 (16%) were chronic users.
And when it works, episodic
content has plenty of advantages.
Telltale Games also frequently has drawn from other popular franchises for other episodic
Positive results from ARISE, the first Phase III study of AMG 334 in episodic
migraine prevention, and results from a Phase II study of AMG 334 in chronic migraine prevention, were announced earlier this year.
Dr Stephen Silberstein, Director of the Thomas Jefferson Headache Center in Philadelphia and former President of the American Headache Society, an author of the paper commented, "This is one of the largest studies of an acute treatment of cluster headache and provides some very encouraging results for patients, particularly those with episodic
cluster, who make up 85 % of all cluster patients.
The clinical implications of these findings, and what I'm stressing, is the importance of intervention --such as psychological counseling--in episodic
migraine patients who have a history of abuse.
Although all migraine patients seen at the Stanford center are encouraged to pursue RLB, only 6% of the chronic migraine group did so regularly, compared with a 10-fold higher rate among those with episodic
The brain recordings in this study, where more than 600 medial temporal lobe neurons were identified, took five years and involved showing the patients pairs of unrelated pictures, one of a person and another of a place, to construct a meaningful association modeling the episodic
memory of meeting a person in a particular place, said study first author Matias J.
Of those with chronic migraine, only 35% reported having at least a bachelor's degree, compared with 46% of those with episodic
migraine (odds ratio, 0.
Preventive pharmacologic treatments for episodic
migraine in adults.
The Colbert Report won the Best Comedy/Variety Series, while the first part of 30 Rock's double-bill finale was named Best Episodic
Comedy on Saturday.