Although GA is a benign epithelial proliferation
, other factors secondary to GA, such as stones, cholecystitis among others may lead to cancer and dysplastic changes.
Moreover, in addition to their neural support roles, glial cells of the ENS also contribute to intestinal epithelial proliferation
and repair after injury through the secretion of proepidermal growth factor (pro-EGF) [72, 73].
Excessive epithelial proliferation
was observed on day 7 in group I whereas, others showed epithelization after day 14.
Cells of epithelial proliferation
had pale eosinophilic cytoplasm and rounded monomorphic nucleus.
Studies show that intraductal epithelial proliferations
are the most important risk factors [1-3].
One study showed that in rats, injection of nickel sulfate (NISO4) induced the epithelial proliferation
in the thyroid glands (16).
Their topics include the origin of the intestinal epithelium, gastrointestinal neoplasms and clonal succession, identifying intestinal stem cells, the role of the epithelial stem cells in restoring damaged epithelium, and molecular mechanisms regulating epithelial proliferation
"Altered prostatic epithelial proliferation
and apoptosis, prostatic development and serum testosterone in mice lacking cyclin-dependent kinase inhibitors," Biology of Reproduction 73(5): 951-958.
The primary study end point was change in Ki-67 index, a widely used measure of epithelial proliferation
. Ki-67 levels were elevated in both treatment and control groups at baseline, which was to be expected in light of the known elevated risk of contralateral breast cancer in women with a history of breast cancer.
The phases of partial thickness wound repair include the inflammatory response, epithelial proliferation
and migration, and re-establishment of the epidermal layers.
Odontogenic epithelial proliferation
is correlated with COX-2 expression in dentigerous cyst and ameloblastoma.
This effect has been mainly attributed to increased epithelial proliferation
and migration induced via the extracellular signal-regulated kinase (ERK) pathway .