Mucosal involvement in a situation in which erythema multiforme
is caused by herpes simplex must be taken into consideration when differentiating between erythema multiforme
and Stevens-Johnson syndrome (2, 3, 10).
(EM), a hypersensitivity reaction usually triggered by infections (most commonly herpes simplex virus), also may appear morphologically similar to SSLR.
with oral erosions was the ADR observed in both.
Annular urticaria responds to combinations of anti-histamines or occasionally steroids; erythema multiforme
requires a detailed history to determine underlying causes, removal or treatment of those causes, and consideration of steroid therapy if indicated.
Incorrect diagnoses occur mainly because many diseases are mistakenly diagnosed as spider bites, including many conditions much more prevalent and serious, such as staphylococcal or streptococcal infection, herpes simplex and zoster, erythema multiforme
, diabetic ulcer, fungal infection, pyoderma gangrenosum, lymphomatoid papulosis, syphilis, and Lyme disease.
During the vaccination program, no cases of eczema vaccinatum, erythema multiforme
major, fetal vaccinia, posrvaccinial encephalitis or encephalomyelitis, or progressive vaccinia have been reported (Table 1).
Stevens-Johnson syndrome, blistering erythema multiforme
, and .toxic epidermal necrolysis are life-threatening reactions to certain medications or herpes simplex infections that are characterized by extensive blistering and widespread loss of the epithelium.
"We know that 90% of cases of erythema multiforme
are related to herpetic infections," but this patient had no recent history of herpes simplex outbreaks, Dr.
Lupus erythematosus associated with erythema multiforme
: Does Rowell's syndrome exist?
The differential diagnosis for EC includes EH, impetiginized atopic dermatitis, varicella, and erythema multiforme
The differential diagnosis includes erythema multiforme
, herpes simplex, and Crohn's disease.