13,38) Mild erythroblastosis
of fetal blood was 3 times more common in placentas with other hypoxic lesions than it was in those placentas without them.
3] Human genes: ETS, v-ets erythroblastosis
virus E26 oncogene homolog 1 (avian); PTEN, phosphatase and tensin homolog; ERG, v-ets erythroblastosis
virus E26 oncogene homolog (avian); BRCA1, breast cancer 1, early onset; BRCA2, breast cancer 2, early onset.
6] Human genes: PCA3, prostate cancer antigen 3 (non-protein coding); TMPRSS2, transmembrane protease, serine 2; ERG, v-ets erythroblastosis
virus E26 oncogene homolog (avian); ETV, ets variant; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.
5) cells in decidua basalis Erythroblastosis
of 16 (9.
Slides were evaluated to determine the presence and extent-severity index of HEV, villitis of unknown etiology, fetal-placental vessel thrombi, villous fibrosis, and erythroblastosis (nucleated red blood cells within chorionic and/or umbilical vessels), and the presence of lesions indicative of maternal hypertension, including primary infarcts, changes described by Tenney and Parker, (13) decidual atheromatosis, decidual thrombi, and ischemic decidual necrosis.
To determine if the association between HEV and perinatal complications was related to the presence of coexistent lesions, incidences of perinatal complications with increasing HEV extent-severity indices were evaluated in placentas with and without coexistent villitis of unknown etiology, fetal-placental vessel thrombi, villous fibrosis, primary infarcts, and erythroblastosis (Table 4).
6] Human genes: hTERT, human telomerase reverse transcriptase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; RPLPO, ribosomal protein, large, P0; UBC, ubiquitin C; ETS2, v-ets erythroblastosis
virus E26 oncogene homolog 2 (avian); uPA, urokinase plasminogen activator; HTATIP2, HIV-1 Tat interactive protein 2, 30kDa; UPKIA, moplakin 1A.
An increase in amniotic fluid bilirubin concentration after 25 weeks indicates extensive hemolysis of fetal blood and potential erythroblastosis
fetalis in which amniotic fluid bilirubin can reach ~10 mg/L (2,3).
Rh isoimmunization and its severe manifestation, erythroblastosis
fetalis, are associated with intrauterine hemolysis, which leads to increases in amniotic fluid bilirubin concentrations (2) up to 9.
Analysis of bilirubin became critical when newborns with an Rh incompatibility to the mother were born with erythroblastosis
fetalis and a rapidly developing hemolytic jaundice to be treated by exchange transfusion.
The amber tube is required if the measurement of amniotic fluid bilirubin is anticipated, as in a case of erythroblastosis
fetalis, before the treatment of Rh-negative mothers with anti-Rh immune globulin, provided us with experience with hyperbilirubinemia and its effect on the brain.