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"We're still active, but, like Vladimir and Estragon, we know about aches and pains!" Stewart adds: "Ian and I are both Northerners, separated only by the Pennines, and I think there's another element there that gives us a shared understanding for the play." Since Godot's British premiere in 1955, which led Harold Hobson, a drama critic of the Sunday Times, to call it "the most unforgettable and important" night of his theatergoing life, the play has been staged in more than 100 countries.
Estragon's unconsciously-uttered statements have a close connection with their previous social life and identity:
Estragon (Richard Heap) and Vladimir (Peter Cadden) swap philosophies, criticisms and insults as they wait for the enigmatic Godot.
The SERDs are believed to hold a promising potential for the treatment of hormone receptor-positive breast cancer and other cancers associated with the estragon receptor.
In this regard it is worth revisiting the conversation of Vladimir and Estragon who engage in pointless conversation with Pozzo and Lucky periodically turning up to inform the two protagonists that Godot will come tomorrow, but Godot never shows up.
Often compared to "a piece of jazz music, to which everyone must listen for whatever one may find in it" (Esslin, xv), in En Attendant Godot Beckett sketches the portraits of two tramps, named Vladimir and Estragon, who are waiting in an open road for a mysterious personage, Godot.
"Where do you go from here?" the immortal words of the two geezers - Estragon and Vladimir - the main characters of Samuel Beckett's Waiting for Godot, perhaps best describe the play that cannot be defined in one simple explanation.
In "Waiting for Godot," the friendship between Vladimir (Stewart) and Estragon (McKellen) is the only thing that's keeping Western civilization from sinking back into the primordial mud.
McKellen playe a d Estragon and Stewart Vladimir in Waiting for Godot at the Theatre Royal in London's West End four years ago.