ethyl chloroacetate

ethyl chloroacetate

[¦eth·əl ‚klȯr·ō′as·ə‚tāt]
(organic chemistry)
CH2ClCOOC2H5 A colorless liquid, boiling at 145°C; used as a poison gas, solvent, and chemical intermediate.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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Then ethyl chloroacetate (1.22 mL, 0.01 mole) was added to the reaction mixture and stirred for 6 h.
After complete addition, stirring of the reaction mixture was continued for 6 h Then ethyl chloroacetate (1.22, 0.01 mol) was added to the mixture and stirring continued for 3 h, then the mixture was poured into crushed ice and HCl; the resulting precipitate was filtrated off, dried, and recrystallized from the appropriate solvent to give 19a,b.
Utility of activated nitriles in the synthesis of novel heterocyclic compounds with antitumor activity
A mixture of phenyltetrazole 5 g (0.03 mol) in methanol is prepared, stirred well to dissolve compound 2.To this add 3.67 mL (0.03 mol) of ethyl chloroacetate drop wise with continuous stirring to get clear solution.
Synthesis and biological activities of some 3-chloro-4-(substituted phenyl)-1-{[2-oxo-2-(5-phenyl-1H-tetrazol-1-yl) ethyl] amino} azetidin-2-one as potential antibacterial agents
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