To find out the suitable components for dexibuprofen microemulsion, the solubility of dexibuprofen in oil (ethyl oleate), surfactants (Tween 40,60, and 80 and triethanolamine), and cosurfactant (PG, PVA, PEG 400, and ethanol) was determined through method reported by Roni and Jalil .
The solubility was also determined in oily mixture of ethyl oleate, Tween 80: PG in a ratio of 1: 10 : 5 according to the method reported by Chen et al.
We quantified 9 FAEE (ethyl laurate, ethyl myristate, ethyl linolenate, ethyl palmitoleate, ethyl arachidonate, ethyl linoleate, ethyl palmitate, ethyl oleate, and ethyl stearate), EtG, and EtS from a single 0.1-g meconium sample with a validated LC-MS/MS method (26).
An exceptionally strong correlation ([rho] [greater than or equal to] 0.9) was seen between FAEE summations and ethyl linoleate and ethyl oleate, indicating that these analytes dominated summation calculations.
Triolein + Ethanol [left and right arrow] Diolein + Ethyl Oleate
At least five lines of chemical inquiry dead-ended before the researchers focused on ethyl oleate
as a potential pheromone component, Robinson says.
For the AOSA compounds synthesized, ethyl oleate
succinic anhydride (EOSA) showed sizing efficiency similar to that of ASA for handsheets prepared with 20% PCC filler.
Ethyl palmitate, ethyl stearate, and ethyl oleate
were unambiguously identified in hair samples from three alcoholics (22).
A very sensitive and specific method for the quantitative analysis of ethyl myristate, ethyl palmitate, ethyl oleate
, and ethyl stearate from hair was developed and applied to hair samples from human fatalities with verified excessive alcohol abuse, moderate social drinkers, and teetotalers (12).
Specifically, the following have been shown: (a) the enzymatic parameters for FAEE synthesis by acyl-CoA:ethanol acyltransferase in human and rat liver microsomes are similar (11,12 ); (b) FAEEs and FAEE synthase are found in rat and human adipose tissues after ethanol intake with a similarly long half-life of -16 h after cessation of ethanol intake (13,14); (c) ethyl oleate
as a representative FAEE in both human and rat LDL is degraded similarly by rat liver, and the oleate is directed after hydrolysis toward triglycerides in both humans and rats (1015); (d) ethyl oleate
as a representative FAEE within human LDL was degraded in both human and rat blood over a 30-min incubation (10).
Single-ion monitoring was performed, quantifying appropriate base ions for individual FAEE species [i.e., ions m/z 67, 88, and 101 for ethyl palmitate (E16:0), ethyl heptadecanoate (E17:0), ethyl stearate (E18:0), ethyl oleate
(E18:1), and ethyl linoleate (E18:2); and ions m/z 79 and 91 for ethyl arachidonate (E20:4), ethyl eicosapentaenoate (E20:5), and ethyl docosahexaenoate (E22:6)].
and ethyl arachidonate substantially inhibited the proliferation of HepG2 cells, while native LDL and LDL reconstituted with cholesterol esters or triglycerides had no effect (Fig.