He has studied various aspects of diabetes-related birth defects from causation to treatment strategies aimed at achieving euglycemia
during early pregnancy and--better yet--before pregnancy.
Wright and colleagues also determined that hyperinsulinemic euglycemia
produced a significant decrease in von Willebrand factor from baseline in the diabetic group, indicating a vasculo protective effect.
In light of the above findings, it was the purpose of this study to measure the in vivo pilocarpine-induced sweat rate during hypoglycemia, euglycemia
, and hyperglycemia.
Diabetic management during labor and delivery is aimed at maintaining maternal euglycemia
to avoid neonatal hypoglycemia.
Diltiazem poisoning treated with hyperinsulinemic euglycemia
therapy and intravenous lipid emulsion.
Studies have demonstrated that acute hyperglycemia is associated with reduced spontaneous coronary perfusion and impaired tissue perfusion as compared to euglycemia
without becoming hypoglycemic has been the challenge to most clinical research studies.
In non-diabetic subjects after carbohydrate ingestion, glucagon release is inhibited and the stimulation of insulin secretion establishes an equilibrium that maintains euglycemia
lc] in nondiabetic patients indicate that even euglycemia
and/or brief periods of hyperglycemia cause glycosylation of hemoglobin A and result in accumulation over time.
In this article we discuss data demonstrating an anti-inflammatory effect of insulin and a pro-inflammatory effect of glucose and free fatty acids and provide a mechanistic justification for the benefits of maintaining euglycemia
with insulin infusions in the hospitalized patient.
The hyperinsulinemic-euglycemic clamp was performed (0-120 min) by a continuous infusion of human insulin (3 mU/kg/min) (Actrapid, Novo Nordisk, Bagsvaerd, Denmark), and euglycemia
(~ 115 mg/dL) was maintained by variable infusion rates of a 20% nonlabeled glucose solution [glucose infusion rate (GIR)].
Supplementation with chromium does not appear to reduce glucose levels in euglycemia