biopsy

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biopsy

(bīäp`sē), examination of cells or tissues removed from a living organism. Excised material may be studied in order to diagnose disease or to confirm findings of normality. Preparatory techniques depend on the nature of the tissue and the kind of study intended. Incisions may be made and total or partial lesions removed in the form of wedges or cylindrical pieces, or scrapings of the surface membranes of internal organs may be collected. Needlelike instruments may be used to pierce the tissues and remove soft inner material. Once the tissue specimen has been obtained it is fixed, i.e., membrane proteins and enzymes are stabilized and chemical and histologic analyses are carried out by pathologists. Tumors are routinely biopsied in order to determine whether they are malignant. Fine needle aspiration is a technique more readily used for certain tumors or lesions because it is less expensive and damaging than traditional surgical biopsy.
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biopsy

[′bī‚äp·sē]
(pathology)
The removal and examination of tissues, cells, or fluids from the living body for the purposes of diagnosis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

biopsy

1. examination, esp under a microscope, of tissue from a living body to determine the cause or extent of a disease
2. the sample taken for such an examination
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
In the case of the patient with the collision tumor, the grossly apparent mass (a well-demarcated 1.2 x 1.1 x 1.0-cm firm area within a 3.5 x 2.5 x 1.5-cm excisional biopsy) was predominantly composed of a 1.0-cm GCT.
One hundred twenty-three cases (71.1%) of invasive ductal carcinoma were identified in lumpectomy or excisional biopsy specimens that had inked operative margins and either intraoperative reexcisions (cavity margins) or delayed reexcision or mastectomy.
(48) If intraepithelial proliferations such as rigid bridges (arcades) or micropapillary structures focally become apparent in deeper levels, the lesion should be diagnosed as ADH, and an excisional biopsy needs to be performed.
Twenty nonconsecutive patients with a primary diagnosis of LCIS and/or ALH diagnosed by NCB who underwent a subsequent excisional biopsy were obtained from the consultation and surgical pathology files of New York Presbyterian Hospital-Weill Medical College of Cornell University (New York, NY).
Formalin-fixed, paraffin-embedded lingual tissue sections from the second excisional biopsy (horizontal glossectomy) were studied using histologic (hematoxylin-eosin) and immunohistochemical methods.
All patients underwent excisional biopsy. Clinical follow-up data was also obtained.
Although their work predated widespread percutaneous core biopsy, these authors found that greater than 10 lobules containing LCIS on surgical excisional biopsy predicted for future development of invasive tumor.
Since occurrence of melanoma is restricted to skin, mouth, intestines or eyes, the diagnostics of melanoma comprises of multiple tests & screening methods such as excisional biopsy, lymph node status analysis, shave biopsy, and fine needle aspirate test.
"After an owner or their veterinarian notices an oral mass, diagnosis usually starts with incisional biopsy, which is typically preferred over excisional biopsy. Histopathology hopefully will yield a diagnosis.
Once you've decided to biopsy, a narrow excisional biopsy with saucerization and 1- to 3-mm margins is preferred when there's a high suspicion for melanoma, said Dr.
Excisional biopsy was performed with BLES in women who had moderate-severe anxiety due to the possibility of breast cancer and a BIRADS 3 breast lesion of <2 cm in diameter as diagnosed by US.