exotoxin


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exotoxin

[¦ek·sə¦täk·sən]
(microbiology)
A toxin that is excreted by a microorganism.
References in periodicals archive ?
Mechanism of action of Pseudomonas aeruginosa exotoxin Aisadenosinediphosphate-ribosylation of mammalian elongation factor 2 in vitro and in vivo.
The cardiac involvement in diphtheria is through the exotoxins produced by these microorganism1,10.
Mitchell, "Campylobacter concisus and exotoxin 9 levels in paediatric patients with Crohn's disease and their association with the intestinal microbiota," Journal of Medical Microbiology, vol.
Mutational analysis of superantigen activity responsible for the induction of skin erythema by streptococcal pyrogenic exotoxin C.
FitzGerald et al., "Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients," Journal of Immunology, vol.
Sterility assessment of multiple use botulinum A exotoxin vials: a prospective simulation.
aeruginosa Genes Primer sequences Amplicon Specification for amplification size (5' to 3') [bp] exoA F: AAC CAG CTC AGC CAC ATG TC 396 detection of R: CGC TGG CCC ATT CGC exotoxin A TCC AGC GCT encoding gene exoS sequence F: GCG AGG TCA GCA GAG TAT CG 118 detection of R: TTC GGC GTC ACT GTG GAT GC exotoxin S encoding gene sequence exoT F: AAT CGC CGT CCA ACT GCA TGC G 152 detection of R: TGT TCG CCG AGG TAC TGC TC exotoxin T encoding gene exoY sequence F: CGG ATT CTA TGG CAG GGA GG 289 detection of R: GCC CTT GAT GCA CTC GAC CA exotoxin Y encoding gene sequence exoU F: CCG TTG TGG TGC CGT TGA AG 134 detection of R: CCA GAT GTT CAC CGA CTC GC exotoxin U encoding gene sequence sequence Abbreviations as in Table 2.
SLO is a well-characterized oxygen-sensitive prototype of a cholesterol-dependent bacterial exotoxin that oligomerizes to form large pores in host cell membranes.
Among these, the genes associated with lipopolysac-charides (LPS), cell wall, multi-drug efflux pumps, protease, exotoxin A, hemolysin, type II secretion system, attachment, motility, chemotaxis and biofilm formations, are more interesting [12, 13].
This exotoxin has a membrane damaging effect not only on erythrocytes, but also on lymphocytes [5], neutrophils, platelets [6], tumor cells [7] and subcellular organelles [8, 9].