Extravasation

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extravasation

[ik‚strav·ə′sā·shən]
(geology)
The eruption of lava from a vent in the earth.
(medicine)
The pouring out or eruption of a body fluid from its proper channel or vessel into the surrounding tissue.

Extravasation

 

the accumulation of blood that has flowed out of the blood vessels into the body cavities or surrounding tissues.

Extravasation may occur when the walls of the vessels are destroyed by a mechanical injury or a pathological process (for example, tumor). It may also occur through an uninjured wall, when the permeability of the wall is increased (for example, under the influence of certain chemical substances). The discharged blood may either permeate the tissues affected by the extravasation or form a circumscribed accumulation, called a hematoma. The significance of extravasation is determined by dimensions, rapidity of development, and site of formation. When the process is minor it is resorbed without treatment. If encapsulated or suppurative, it often requires special treatment. Because extravasation may lead to the destruction of tissue, it is especially dangerous in the brain (insult).

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The FDA recently cleared ivWatch Model 400 from ivWatch, LLC, a first-of-its-kind continuous monitoring device that will improve patient care by quickly detecting common adverse events: IV infiltration and extravasation.
Selection of the main renal artery showed multiple areas of small pseudoaneursym formation and active extravasations with AV fistula formation in the interpolar to upper polar region of the right kidney (Figure 2).
Schulmeister adds that "infusion pumps should not be used to administer vincristine peripherally as they deliver infusions at higher pressures than gravity infusions and may continue to infuse even though extravasation is occurring.
COPENHAGEN, February 5 /PRNewswire/ -- New guidelines published by the European Oncology Nursing Society (EONS) offer a practical guide to extravasation management and recommend Savene(R) (dexrazoxane) as the only approved therapy in the treatment of this condition.
The patented system prevents moderate to severe contrast extravasations that may seriously injure patients.
We are extremely pleased to add Savene([R]) to our product portfolio and are confident SpePharm will continue to rapidly grow its sales as we integrate this medically important orphan drug product for the treatment of patients with anthracycline extravasations into our portfolio.
Both the IRiSCT and EmpowerMR systems track extravasations with the Extravasation Detection Accessory (EDA).
We are pleased that the INS, a group of professionals on the front lines of patient care, has clearly and accurately cited Totect[R], the only FDA-approved antidote for anthracycline extravasations," said John L.
announced today that its XDS(TM) Extravasation Detector has received a 2008 Medical Design Excellence Award(R) (MDEA).
8-11) Most extravasations in our practice involve small volumes (<50 mL).
All extravasations were asymptomatic with no cardio-pulmonary complications.
Patented Product Senses Extravasations in CT Procedures with Direct Detection Technology