Berrebi A, Malnick SDH, Vorst EJ, et al High incidence of
factor XI deficiency in Gaucher's disease.
Factor XI deficiency results in a lower incidence of thromboembolic events with minimal increase in bleeding risk.
There are many enigmas regarding the etiology and treatment of
factor xi deficiency.
Vtgs 1 and 2, choriogenins 2 and 3, ER[alpha], and coagulation
factor XI increased in a concentration-dependent manner in the E[E.
Until a genetic abnormality is established, evaluation of factor VIII and possibly
factor XI coagulant levels may be useful in patients in whom no other abnormalities are detected.
Having excessive amounts of
factor XI itself may not be enough to lead to such a troublesome clot, says study coauthor Joost C.
Factor XI deficiency was found in nine families (n=10), 2.
Of 150 women referred to one clinic, 26 (17 per cent) were found to have either lack of clotting
factor XI or abnormal blood platelets, which is easily diagnosed with blood tests.
29 May 2014 - Canadian biological diagnostic and research products maker Affinity Biologicals Inc said Thursday it had recently launched four Visulize ELISA Kits that are able to quantitatively and qualitatively evaluate Factor VIII, Factor IX,
Factor XI and TAFI antigens in human plasma samples.
Our testing revealed, however, that only the 1:10 dilution (1 volume of sample in 9 volumes of diluent) revealed a low
factor XI activity, and the
factor XI activity increased with dilution, such that a 1:40 dilution (1 volume sample in 39 volumes diluent) had normal
factor XI activity.
