Case--control study evaluating relationship of blood pressure and anthropometric parameters with nonalcoholic fatty liver disease
. Natl J Physiol Pharm Pharmacol 2018;8(8):1128-1134.
The condition, known as non-alcoholic steatohepatitis, or NASH, is a more advanced form of fatty liver disease
, which features inflammation of the liver.
Judi Rhys, chief executive of the British Liver Trust, said: "This study indicates that the UK prevalence of NASH - the more serious form of fatty liver disease
- could be significantly higher than we thought, and potentially even higher than type 2 diabetes in this population.
'With the rise in childhood obesity, we are seeing more kids with nonalcoholic fatty liver disease
in our pediatric weight management practice,' said Jennifer Woo Baidal, lead author of the paper.
While the disease is generally symptomless, progression of non-alcoholic fatty liver disease
can lead to cirrhosis scarring of the liver and in some cases liver cancer.
The phase 2a is a multi-centre, proof-of-principle and open-label study designed to evaluate the efficacy, safety, and tolerability of MN-001 in subjects with non-alcoholic steatohepatitis or non-alcoholic fatty liver disease
Her past medical history included nonalcoholic fatty liver disease
, hypertension, hyperlipidemia, obesity, iron deficiency anemia, and colon polyps.
Non-alcoholic fatty liver disease
is a term used to cover a range of conditions and illnesses caused by a build up of fat in the liver.
An article published in 2010 in The New England Journal of Medicine indicated that people with non-alcoholic fatty liver disease
are more likely than those without it to have build-ups of cholesterol-filled plaque in their arteries, the blood vessels that supply the heart.
Nseir, "Advanced hepatic fibrosis in fatty liver disease
linked to hyperplastic colonic polyp," Canadian Journal of Gastroenterology and Hepatology, vol.
Cammarota, "Gut microbiota as a driver of inflammation in nonalcoholic fatty liver disease
," Mediators of Inflammation, vol.
Nonalcoholic fatty liver disease
(NAFLD) is the most common cause of chronic liver disease that affects 20-30% of adults and 10% of children especially in industrialized countries, the prevalence of which is increasing all over the world.