feedback inhibition


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Related to feedback inhibition: Allosteric regulation

feedback inhibition

[′fēd‚bak ‚in·ə‚bish·ən]
(biochemistry)
A cellular control mechanism by which the end product of a series of metabolic reactions inhibits the activity of the first enzyme in the sequence. Also known as allosteric control.
References in periodicals archive ?
Other compounds that may cause feedback inhibition of nitrogenase activity in nodules are amino acids, such as asparagine (Oti-boateng and Silsbury, 1993; Bacanamwo and Harper, 1997; Serraj et al., 1999b;) or glutamine (Neo and Layzell, 1997).
Females and Males of Reproductive Potential - During treatment with large doses of exogenous androgens, including JATENZO, spermatogenesis may be suppressed through feedback inhibition of the hypothalamic-pituitary-testicular axis.
In Arabidopsis, the removal of feedback inhibition of an enzyme from the proline metabolism resulted in a high accumulation of this osmolyte (52 mmol [g.sup.-1] FW, approximately 300% when compared to the control), which provided increases in the plant tolerance to osmotic stresses (Hong et al., 2000).