Auryxia (ferric citrate
) net product revenue increased 20.7 percent year-over-year to $29.1 million for the second quarter of 2019, and increased 26 percent when compared with the first quarter of 2019.
AkebiaCares provides patients, caregivers and health care providers with resources and important information to support greater access to Auryxia (ferric citrate
Not everybody has the same iron requirement, however, but multivitamins typically contain about 18 mg of ferrous sulfate, ferric citrate
, ferrous gluconate or ferric sulfate.
Bacterial culture medium was made up of 2216E marine agar, 5 g peptone, 1 g yeast powder, 0.1 g ferric citrate
, 15-20 g powdered agar, 1000 mL seawater (pH 7.2-7.5).
Keryx's Auryxia (ferric citrate
) is a US Food and Drug Administration -approved medicine to treat dialysis dependent CKD patients for hyperphosphatemia and non-dialysis dependent CKD patients for iron deficiency anemia.
Keryx announced that data from an investigator sponsored study that evaluated the use of ferric citrate
in patients with advanced chronic kidney disease, or CKD, was presented as a late-breaking oral presentation at the 55th annual ERA/EDTA congress in Copenhagen.
According to Chalmers University of Technology-led study, two compounds, ferric citrate
and ferric EDTA, are often used in dietary supplements and as a food additive respectively, in worldwide markets including the USA and the EU, increase the formation of a known biomarker for cancer.
Several compounds, such as ferric citrate
, iron-magnesium hydroxycarbonate, and sucroferric oxyhydroxide, have undergone clinical trials for evaluation of efficacy and safety (Negri & Torres, 2014).
Bacterial isolates were first sub-cultured from stock cultures on Marine Agar Medium containing (per liter): 5.0 g peptone, 1.0 g yeast extract, 0.1 g ferric citrate
, 19.45 g NaCl, 8.8 g magnesium chloride, 3.24 g sodium sulfate, 1.8 g calcium chloride, 0.55 g potassium chloride, 0.16 g sodium bicarbonate, 0.08 g potassium bromide, 34.0 mg strontium chloride, 22.0 mg boric acid, 4.0 mg sodium silicate, 2.4 mg sodium fluoride, 1.6 mg ammonium nitrate, 8.0 mg disodium phosphate, 15.0 g agar and pH 7.0.
LAS VEGAS--Treatment with ferric citrate
coordination complex conferred multiple benefits with cardioprotective implications in non-dialysis-dependent chronic kidney disease patients with elevated serum phosphate and iron-deficiency anemia in a randomized trial.
Keryx is developing Zerenex (ferric citrate
), an oral, ferric iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes.