fertility drug


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Related to fertility drug: Clomid

fertility drug,

any of a variety of substances used to increase the possibility of conception and successful pregnancy. Different methods are used to correct or circumvent the many different functional disorders of both males and females that can interfere with conception and childbearing (see infertilityinfertility,
inability to conceive or carry a child to delivery. The term is usually limited to situations where the couple has had intercourse regularly for one year without using birth control.
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). The term fertility drug primarily refers to drugs that mimic or stimulate production of a hormone necessary for conception, but it may also be used to refer to the hormones themselves, when they are administered as part of a program of infertility treatment.

The most common cause of female infertility is failure to ovulate. In certain cases this can be corrected with the drug clomiphene citrate (Clomid, Serophene). Introduced in 1967, clomiphene stimulates the release of the gonadotropic hormonesgonadotropic hormone
or gonadotropin,
any one of three glycoprotein (see protein) hormones released by either the anterior pituitary gland or the placenta (the organ in which maternal and fetal blood exchange nutrients and waste products) that have various effects upon
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: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). FSH functions to stimulate the ovarian follicle (the egg and its surrounding fluid and hormones); LH triggers ovulation. In some studies, clomiphene has been associated with an increased risk of ovarian cancer. Clomiphene is also used to stimulate spermatogenesis in men with low sperm counts.

Human menopausal gonadotropin, or menotropin (Pergonal), introduced in 1970, is an extract from the urine of menopausal women. It contains FSH and LH and encourages ovulation. It is often given together with human chorionic gonadotropin (HCG), a hormone secreted by the placenta during pregnancy and obtained from the urine of pregnant women. Its action is similar to that of luteinizing hormone. In males the same combination is given to increase testosterone production, which in turn increases sperm production.

Urofollitropin (Metrodin) is essentially follicle-stimulating hormone without luteinizing hormone. It is used especially in women with polycystic ovary syndrome, who tend to have too little FSH and too much LH. A frequent result of ovulation induced by these drugs is the production of more than one ovum (egg) in a month, and subsequent multiple birthsmultiple birth,
bringing forth of more than one offspring at birth. Although many smaller mammals bear several young at a time, multiple births are relatively uncommon in humans and other primates.
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.

Progesteroneprogesterone
, female sex hormone that induces secretory changes in the lining of the uterus essential for successful implantation of a fertilized egg. A steroid, progesterone is secreted chiefly by the corpus luteum, a group of cells formed in the ovary after the follicle
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 is a female sex hormone that induces secretory changes in the lining of the uterus essential for successful implantation of a fertilized egg. It is released by the ovary after the ovum is released. It is administered in cases where fertilization of the ovum does occur but where there is evidence that the uterine lining is unable to support the developing fetus, as in repeated miscarriages or bleeding during pregnancy.

See also DESDES
or diethylstilbestrol
, synthetic nonsteroid female sex hormone having the same physiological effects as estrogen. In the 1940s and 50s DES was mistakenly believed to reduce the risk of miscarriage and was routinely prescribed for pregnant women believed to be at
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 (diethylstilbestrol).

References in periodicals archive ?
We do know that far more multiple births are occurring now than would be expected--were it not for fertility drugs.
Women who are taking fertility drugs should always ask their doctor what they can do to prevent having a multi-fetal pregnancy," Dr.
In fact, a recent, more comprehensive study published in the British Medical Journal that looked at a number of fertility drugs in more detail found no overall increased risk of ovarian cancer, he said.
Patients with PCOS have a very different response to fertility drugs .
I'm horrified to learn that a small number of women yearning for a baby could be risking their health by buying fertility drugs online.
Investigators collected interview data on infertility and fertility drug use from eight case-control studies conducted between 1989 and 1999 in the United States, Denmark, Canada and Australia, including 5,207 women with ovarian cancer, and 7,705 women without ovarian cancer.
Dr Bryan Carroll, deputy director of the zoo, said: "Being able to treat female gorillas with human fertility drugs is potentially a very important breakthrough.
FSH is also a commonly used fertility drug with a global market that is approaching $1 billion annually.
FSH is also used as a fertility drug with a current global market of approximately $800 million/year.
Around 3,500 tablets of the fertility drug were taken from the premises of Dowelhurst, in Wedgenock Lane, Warwick.
For example, as alleged in the complaint, on November 8, 1999, defendants reported that the Company's operating results for its third fiscal quarter improved over the comparable 1998 period, and stated that a Swiss company, Ares-Sereno, had paid $68 million to the Company for the marketing rights to the fertility drug Crinone which was manufactured by Columbia.
MADRID: Hundreds of people carrying torches climbed a hillside during darkness to pay homage to a giant toad, which they say is their answer to the fertility drug Viagra.