fibroblast growth factor


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Related to fibroblast growth factor: Epidermal growth factor, Basic fibroblast growth factor

fibroblast growth factor

[¦fī·brō‚blast ′grōth ‚fak·tər]
(physiology)
A family of proteins important in the development of the nervous and skeletal systems.
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Heparinase activity expressed by platelets, neutrophils, and lymphoma cells releases active fibroblast growth factor from extracellular matrix.
Fibroblast Growth Factor Receptor 1 Amplification in Nonsmall Cell Lung Cancer Epidemiology
5] Nonstandard abbreviations: CA125, cancer antigen 125; HE4, human epididymis protein 4; TGF-0, transforming growth factor 0; FGF, fibroblast growth factor; FGFR, FGF receptor; FGF2, fibroblast growth factor 2; SNP, single-nucleotide polymorphism; MAF, minor-allele frequency; OR, odds ratio; HR, hazard ratio; CART, classification and regression tree (analysis); eQTL, expression quantitative trait loci; Genevar, Gene Expression Variation (database).
Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats.
This press release contains forward-looking statements regarding the progress of ArQule's clinical trial with ARQ 087, an inhibitor of fibroblast growth factor receptor (FGFR).
The team further experimented on zebrafish, and were able to rescue the development of the forelimb-pectoral fin-by treating retinoic acid-deficient embryos with a drug that reduces fibroblast growth factor activity.
Experimenters have also found that a protein called fibroblast growth factor (FGF) speeds nerve growth.
It is a new human monoclonal antibody specific for fibroblast growth factor receptor 3 that is being developed to target FGFR3-positive tumours.
Last year, two groups reported that achondroplasia, the most common genetic form of dwarfism, results from a small mutation in the gene that contains the instructions for fibroblast growth factor receptor 3 (FGFR3), a protein needed for skeletal development in the embryo.
FP-1039 is a fibroblast growth factor (FGF) ligand trap being studied in early stage clinical trials in a variety of cancers
Haluzik's presentation, titled 'Ten Months of Treatment with Endoscopic Duodenal-jejunal Bypass Liner Reduces Glycemic Variability, Increases Serum Fibroblast Growth Factor 19 (FGF-19), and Partially Restores the Incretin Effect in Obese Subjects with Type 2 Diabetes Mellitus,' follows the progress of 30 obese patients with type 2 diabetes after being implanted with the EndoBarrier gastrointestinal liner.