Diagnosis: Superficial [CD34.sup.+] Fibroblastic
In the present study, increase in collagen may be due to more neovascularisation, fibroblastic
proliferation, granulation tissue formation in laser treated wounds.
tissue within airspaces, particularly in alveolar ducts (alveolar duct fibrosis), may be seen in organizing DAD but does not constitute the dominant findings, as in cases of OP.
Nodular fasciitis is an uncommon tumor-like fibroblastic
proliferation known for its propensity to mimic more aggressive lesions.
According to the literature, the immunophenotype heterogeneity and the discordance in the findings observed under electron microscopy can be explained by either the evolution in time of this entity from fibroblastic
, myofibroblastic, to myoid differentiation or by selective sampling, especially on biopsy.
proliferation: 0, No fibroblastic
proliferation; 1, Minimal fibroblastic
proliferation; 2, Moderate fibroblastic
proliferation; 3, Advanced fibroblastic
They had both elongated shapes like fibroblastic
and shapes with more regular dimensions like epithelial cells.
The neoplastic cells include bland spindled to oval fibroblastic
cells in bundles or sheets, and scattered large pleomorphic cells with nuclear pseudoinclusion, low nuclear to cytoplasmic ratios, and moderate to abundant eosinophilic cytoplasm.
Platelets store growth factors including platelet-derived growth factor, transforming growth factor-ss, platelet-derived epidermal growth factor, vascular endothelial growth factor, insulin-like growth factor-1, fibroblastic
growth factor, and epidermal growth factor, cytokines and many other proteins.3 Therefore, increasing platelet concentration in a damaged tissue would result in increased levels of these growth factors and, subsequent, improvement in healing process.4 Its applicability includes plastic surgery,1 orthopedic surgery,3 cardiac surgery, ophthalmology, and sports medicine.5 There are differences in the concentration of platelets prepared by the various automated and manual techniques described in the literature6 and this can affect the different biological effects.
Histology revealed interstitial expansion with fibroblastic
foci and architectural distortion with mild to moderate inflammation, as well as uninvolved foci with alveolar dilatation (Fig.
They are now considered part of a broader class of soft tissue neoplasms of fibroblastic
and myofibroblastic origin and can arise from virtually any part of the body.
Sarcoids are locally invasive, fibroblastic
skin tumors and represent the most common tumor in equids worldwide (Marti et al., 1993).