Fibroin


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fibroin

[′fī·brə·wən]
(biochemistry)
A protein secreted by spiders and silkworms which rapidly solidifies into strong, insoluble thread that is used to form webs or cocoons.

Fibroin

 

a simple protein, the principal component of the natural silk and spider-silk fibers secreted by the silk-secreting glands of certain insects and the silk glands of spiders and other arthropods. Fibroin is a viscous, syrupy fluid, that hardens in the air to a tough, insoluble filament. Fibroin threads, coated with the protein sericin, form a silk fiber, as in silkworm cocoons.

Fibroin belongs to a group of structural proteins called scleroproteins. It is resistant to organic solvents, dilute acids and bases, and proteolytic enzymes. The fibroin molecule consists of an elongated polypeptide chaino with repeating structural units, measuring approximately 7 Å. The group of amino acids in fibroin includes a high content of glycine (43 percent), alanine, serine, and tyrosine. The content of the amino acid tyrosine in fibroin is so much higher than in other proteins that fibroin is usually used as the prime source for obtaining tyrosine.

References in periodicals archive ?
For the co-initiating mechanism of SP, the photofading mechanism of the dye on dyed silk fibroin might give us some suggestions.
Phinyocheep, "Preparation of porous silk fibroin microparticles by a water-in-oil emulsification-diffusion method," Journal of Applied Polymer Science, vol.
Caption: FIGURE 5: ELISA results for interfering antigens to test the specificity of anti-keratin primary antibody: (a) PBS; (b) negative control; (c) BSA; (d) HSA; (e) ovalbumin; (f) collagen; (g) sericin; (h) fibroin; (i) cotton extraction; (j) hemp extraction; (k) wool extraction; (l) keratin.
Lin, "Electrospinning of silk fibroin and collagen for vascular tissue engineering," International Journal of Biological Macromolecules, vol.
Fibroinase is a native silk digestion enzyme characterized as a cysteine proteinase and digests fibroin and sericin [29, 30].
Degummed silk fibroin meshes were integrated with electrospun aligned silk fibroin cores [42].
dipped in a solution of 1% silk fibroin, shelf lite is extended by seven
Called fibroin, it's what gives the spider silk its structure and mechanical stability.
Silk could be key to artificial cardiac tissue--specifically, the protein giving the silk its structure and mechanical stability: fibroin. Prof.
Mineralized silk fibroin composite foams and films display excellent biocompatibility.
Ltd.) won for their work on a "Novel Silk Fibroin Scaffold for Bone Graft Applications." It explores use of silk fibroin, a natural polymer produced by Bombyxmori silk worms to prepare scaffolds for tissue engineering applications.
Preparation and characterization of scaffold nanofibers by electrospinning, based on chitosan and fibroin from Silkworm (Bombyx mori)