Fibrosarcoma

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fibrosarcoma

[¦fī·brō·sär′kō·mə]
(medicine)
A sarcoma composed of spindle cells that produce collagenous fibrils.

Fibrosarcoma

 

an immature malignant tumor of connective tissue; a malignant variant of fibroma, fibromyoma (leiomyoma), or fibroadenoma that can occur in any part of the body. It is characterized by invasive and destructive growth but sometimes has distinct contours. In cross section it looks like fish flesh. A fibrosarcoma has a marked capacity to metastasize, chiefly through blood vessels. It can often be distinguished from a fibroma only by histological examination and is treated surgically.

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Differential diagnosis included gastrointestinal smooth muscle tumor, leiomyosarcoma, fibrosarcoma, and malignant peripheral nerve sheath tumor.
Among malignant neoplasms, squamous cell carcinomas, extragenital transmissible veneral tumors, lymphomas and fibrosarcoma were common and in benign tumors, papilloma, trichoblastoma, mast cell tumor, plasma cell tumor and fibroma were common.
Fibrosarcomas primarily occur in the soft tissues, but intraosseous lesions have also been reported.
The young age of the macaw was unusual compared with the pattern in dogs; however, fibrosarcomas were described in budgerigars as young as 1 year of age, (12) in a 1-year-old canary (Serinus canaria), (6) a 6-week-old chicken, (4) and a 5-year-old blue-and-gold macaw.
Posteriormente se describio un fibrosarcoma en Gadus morhua (36) y carcinomas embrionarios en Esox lucius (12).
Radiologically, the differential diagnosis includes neurogenic tumors, minor salivary gland tumors, dermoid or epidermoid tumors, hemangiomas, sarcoidosis, aggressive fibromatosis, dermatofibromas, fibrosarcomas, and malignant histiocytomas.
5,16) Despite the controversy over the terminology, definition and criteria used for the diagnosis of IMFT and inflammatory fibrosarcoma, (6,16) there is growing consensus that they are an interrelated myofibroblastic continuum, typified by a spectrum of histomorphological features and potentially aggressive behaviour and shared clinicopathological features.
Bilateral subcutaneous fibrosarcomas in a cat following feline parvo-, herpes--and calicivirus vaccination.
Long-term survival was registered in these PDT-treated groups only in animals with CR of G:5:1:13 fibrosarcomas.
He added that pathologists "need to be sharp on this [diagnosis]," noting that in the past, many have overdiagnosed these as fibrosarcomas or hemangiopericytomas.
Be aware that fibrosarcomas and angiosarcomas are more common--not just in a Stewart Treves [syndrome] kind of picture, where you have chronic edema and then develop an angiosarcoma.