biopsy

(redirected from fine-needle aspiration biopsy)
Also found in: Dictionary, Thesaurus, Medical.

biopsy

(bīäp`sē), examination of cells or tissues removed from a living organism. Excised material may be studied in order to diagnose disease or to confirm findings of normality. Preparatory techniques depend on the nature of the tissue and the kind of study intended. Incisions may be made and total or partial lesions removed in the form of wedges or cylindrical pieces, or scrapings of the surface membranes of internal organs may be collected. Needlelike instruments may be used to pierce the tissues and remove soft inner material. Once the tissue specimen has been obtained it is fixed, i.e., membrane proteins and enzymes are stabilized and chemical and histologic analyses are carried out by pathologists. Tumors are routinely biopsied in order to determine whether they are malignant. Fine needle aspiration is a technique more readily used for certain tumors or lesions because it is less expensive and damaging than traditional surgical biopsy.

biopsy

[′bī‚äp·sē]
(pathology)
The removal and examination of tissues, cells, or fluids from the living body for the purposes of diagnosis.

biopsy

1. examination, esp under a microscope, of tissue from a living body to determine the cause or extent of a disease
2. the sample taken for such an examination
References in periodicals archive ?
Fine-needle aspiration biopsy can also be used to diagnose primary bone and bone marrow tumors of the vertebral column, as well as other nonneoplastic lesions such as Paget disease, degenerative disease, osteoporotic fractures, and amyloidosis, as well as inflammatory conditions involving the vertebra and intervertebral discs.
Findings on fine-needle aspiration biopsy (FNAB) and subsequent pathology of excisional biopsy in the three groups (N = 89) Clinician group Pathologist group n = 58 (65%) n = 20 (22%) FNAB Pathology FNAB Pathology Result (n [%]) 26 (45) 46 (79) 12 (60) 15 (75) Benign 4 (7) 12 (21) 4 (20) 5 (25) Malignant 21 (36) -- 2 (10) -- Suspicious 7 (12) -- 2 (10) -- Nondiagnostic Sensitivity (%) 86 100 Specificity (%) 78 94 Positive predictive 48 83 value (%) Radiologist group n = 20 (22%) FNAB Pathology Result (n [%]) 4 (36) 9 (82) Benign 1 (9) 2 (18) Malignant 6 (55) -- Suspicious 0 (0) -- Nondiagnostic Sensitivity (%) 100 Specificity (%) 44 Positive predictive 29 value (%)
Fine-needle aspiration biopsy of soft tissue sarcoma: a cytomorphologic analysis with emphasis on histologic subtyping, grading, and therapeutic significance.
The role of fine-needle aspiration biopsy in the initial diagnosis of pediatric bone and soft tissue tumors: an institutional experience.
Their new guidelines follow many attempts over the past 15 years to create guidelines for whether to do a fine-needle aspiration biopsy.
In 2009, the American Thyroid Association guidelines for the management of thyroid nodules and DTC advised that upon the detection of a thyroid nodule, every patient should undergo a complete history and physical examination focusing on the thyroid gland, measurement of serum thyroid stimulating hormone (TSH) with radionuclide scan if the value is below normal, and thyroid ultrasound to assess sonographic features, as well to determine the presence of additional nodules and lymphadenopathy, with the subsequent performance of a fine-needle aspiration biopsy (FNAB), as indicated (3).
Needle localization and fine-needle aspiration biopsy of nonpalpable breast lesions with use of standard and stereotactic equipment.
Chen, "Accuracy of fine-needle aspiration biopsy for predicting neoplasm or carcinoma in thyroid nodules 4 cm or larger," Archives of Surgery, vol.
Is fine-needle aspiration biopsy a practical alternative to open biopsy for the primary diagnosis of sarcoma Experience with 140 patients.