fixative


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fixative

1. a fluid usually consisting of a transparent resin, such as shellac, dissolved in alcohol and sprayed over drawings to prevent smudging
2. Cytology a fluid, such as formaldehyde or ethanol, that fixes tissues and cells for microscopic study
3. a substance added to a liquid, such as a perfume, to make it less volatile
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

fixative

[′fik·səd·iv]
(materials)
A chemical or a mixture of chemicals used to treat biological specimens before preservation so as to retain a reasonable facsimile of their appearance when alive.
A substance used to increase the durability of another substance; used to fix dye mordants, hold textile dyes and pigments, and slow the rate of perfume evaporation. Also known as fixing agent.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Fixation parameters that have not yet been evaluated for confounding effects on immunohistochemistry include the size and manipulation of the specimen before immersion (such as sectioning or biopsy procurement ex vivo), the primary method of containment during fixation (eg, a biopsy bag or cassette), and other fixation conditions, such as movement of the specimen within the fixative solution, exposure to light, and the number and relative position of cofixed specimens.
Culling had observed that the choice of a fixative affects histochemical reactions.
Tissue handling is simplified in these areas because the samples need only be divided into light microscopy and EM fixatives.
When copolymerized with other alkyl(meth)acrylates, the polymers are useful hair fixatives. In an extension of this technology, Dow Chemical researchers have found that inclusion of styrene as a co-monomer raises the refractive index and confers shine to the hair, and the inclusion of hydroxyethyl methacrylate enhances the polymer solubility, giving rise to clear fixative solutions that enhance the shine even more.
However, fixative is probably retained internally in tissues, potentially interfering with growth during viability testing.
Three 7 mm punches of grossly benign tissue were harvested from each of 5 radical prostatectomy samples that were subjected to less than an hour of cold ischemic time and then fixed in 10% NBF, Bouin fixative, or Hollande fixative for 12 hours.
Another rotation is taken and this sample is transferred to the liquid fixative. It was centrifuged at 2000 rpm for 5 minutes.
Phosphate-buffered formaldehyde is the most commonly used fixative for light microscopy because of its low cost, high ease of preparation, and good preservation of morphological details with few artifacts (23-25).
Obtained blastemal samples were fixed in six different freshly prepared fixative solutions according to manufacturer's protocols (Suvarna et al., 2013).
* Kneaded erasers, eraser pencils, blending stumps, spray fixative,
When the condition is mild or medium, a conservative treatment could be applied - a fixative between the foot's big and index toes, put in a way so the big toe is aligned properly.