floxuridine


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floxuridine

[‚fläks′yu̇r·ə‚dēn]
(pharmacology)
C9H11FN2O5 Crystals that melt at 150-151°C; used as an antiviral drug and as an inhibitor of deoxyribonucleic acid synthesis. Abbreviated FUDR.
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35) Primary sclerosing cholangitis-like injury is a relatively uncommon pattern that is mainly seen with infusion of chemotherapy agents into the hepatic artery such as floxuridine and fluorouracil to treat metastatic colorectal cancer to the liver, as well as hepatic arterial chemoembolization in hepatocellular carcinoma.
Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: long-term results of a prospective randomized trial.
for the treatment of non-resectable metastatic liver tumors from primary colorectal cancer in combination with intra-hepatic artery chemotherapy using floxuridine.