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It was also identified for the first time that aldo-keto reductase 1C1 (AKR1C1) enhances tumour-promoting activities and proved the enzyme blocks the effectiveness of cisplatin and other anti-cancer drugs, which can be inhibited by flufenamic acid, the researchers concluded in the paper.
Oral antipyretric therapy: Evaluation of the N-arylanthranilic acid derivatives mefenamic acid, tolfenamic acid and flufenamic acid.
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