The main finding of this study is that the osteochondral tissue from focal lesions
, located in the same anatomical region and in patients with similar age and BMI, presented distinct histological and biologic characteristics according to the etiology, which could explain the different healing potential and the different clinical results reported in the literature treating OCD and DL with osteochondral scaffolds.
Interventional radiology studies, such as transhepatic portal venous insulin sampling (54) and selective pancreatic arterial calcium stimulation (51), have been used to localize focal lesions
. Both have only modest success and are technically difficult and highly invasive.
In the first of three studies aimed at determining the value of endometrial vascularity in the prediction of focal lesions
, the presence of endometrial "feeding vessels" was noted in 36 women with postmenopausal bleeding and an endometrial thickness that was greater than or equal to 5 mm.
USG was handy for demonstrating focal lesions
in liver and spleen.
Table 2: Focal lesions
detected with CT and PET and lesions' characteristics.
A ROI of 5 [mm.sup.2] was selected over the periphery and over the centre of the focal lesion
, using the accumulation image.
The ultrasonograph revealed a focal lesion
of the left lobe of the liver, which was solid, partly mixed, and contained a predominantly hyperechoic zone (10 cm in diameter, including some smaller hypoechoic areas and beams spreading radially into the adjacent parenchyma).
His liver was enlarged with a span of 16.6 cm with no other focal lesion
. No perihepatic or pleural effusion was seen.
All three studies provided similar results in predicting any focal lesion
, with an average 90% sensitivity and 92% positive predictive value.
Sonomammography revealed a 2.5x2x1.9cm solid focal lesion
in right breast subareolar region.
A set of two images were obtained for each focal lesion
MRI spine showed focal lesion
is seen in the D9 vertebral body.