Table 1: Comparison of result of thyroid test between FNAC and histopathology findings Diagnosis FNAC, n (%) Histodiagnosis, n (%) Benign lesions Colloid goiter 38 (63.3) 42 (70) Benign thyroid cyst 1 (1.6) 1 (1.6) Thyroglossal cyst 2 (3.3) 2 (3.3) Follicular adenoma
-- 3 (5.0) Hashimoto's thyroiditis 7 (11.6) 6 (10.0) Lymphocytic thyroiditis 1 (63.3) 1 (1.6) Hyalinising trabecular tumour -- 1 (1.6) Other 2 (3.3) -- Total 51 (85.0) 56 (93.3) Malignant lesions Papillary carcinoma 3 (5.0) 3 (5.0) Anaplastic carcinoma 1 (1.6) 1 (1.6) Other 5 (8.3) -- Total 9 (15.0) 4 (6.6) Table 2: Correlation between cytodiagnosis and histodiagnosis Cytological diagnosis Histological diagnosis No.
TABLE 1: Comparison of mean age and size amongthe 231 thyroid nodules diagnosed as follicular adenoma
, follicular carcinoma, and follicular variant of papillary thyroid carcinoma.
However, this is not a good yardstick for FNAC of the thyroid as a large group falls in the category of suspicious or consistent with follicular neoplasm, out of which the majority turn out to be follicular adenomas
or hyperplastic/adenomatous nodules.
was the most common benign tumour (8 cases - 11.11%) which correlated with studies conducted by Gupta et al  (16%), Silverman et al  (5.2%) and Sathiyamurthy et al  (5.45%), but higher than Handa et al  (1.84%).
A subtotoal thyroidectomy was performed because of the compressive symptoms, which indicated a follicular adenoma
(10,11) Follicular adenoma
, on the other hand, is usually a solitary nodule discovered in a euthyroid gland.
The histopathological findings were classified into six groups: Nodular goitre, thyroiditis, benign tumors (follicular adenomas
), malignant tumors, Primary thyrotoxicosis, and others.
Among the other 7 patients in the hypothyroid group, 4 (28.6%) had a diagnosis of follicular adenoma
, 2 (14.3%) had multinodular goiter, and 1 (7.1%) had diffuse atrophy and scar tissue on the thyroid gland (table 1).
was present in 24% of the patients.
Many neoplasms are considered in the differential diagnosis, but the principal ones are follicular adenoma
, follicular carcinoma, and medullary carcinoma; nonneoplastic considerations are diffuse hyperplasia (Graves' disease) and adenomatoid nodules.
& thyroid carcinoma are the third most common type (4.2% each).
Immunohistochemical separation of follicular variant of papillary thyroid carcinoma from follicular adenoma
. Endocr Pathol.