Primary gastrointestinal follicular lymphoma
involving the duodenal second portion is a distinct entity: a multicenter, retrospective analysis in Japan.
The US FDA FTD for Betalutin (177Lu-lilotomab satetraxetan) is based on the company's PARADIGME study for the treatment of patients with relapsed or refractory follicular lymphoma
(FL) after at least two prior systemic therapies.
The differential diagnosis includes not only secondary cutaneous involvement by a systemic follicular lymphoma
but also reactive lymphoid hyperplasia and other types of cutaneous B-cell lymphomas.
Franck Morschhauser, M.D., Ph.D., from the University of Lille in France, and colleagues conducted an international, randomized phase 3 trial to evaluate rituximab plus lenalidomide (513 patients) versus rituximab plus chemotherapy (one of three rituximab-based regimens; 517 patients) in patients with previously untreated follicular lymphoma
. Both regimens were followed by rituximab maintenance therapy.
The main histological subtypes of non-Hodgkin's lymphoma are the diffuse large B-cell lymphoma, follicular lymphoma
, and Burkitt lymphoma [9-11].
(FL) is the second most common non-Hodgkin's lymphoma.
Last Thursday, Emily was diagnosed with follicular lymphoma
, a type of blood cancer that attacks the white blood cells, or lymphocytes, in the bloodstream.
The company has developed engineered cell therapies that express either a chimeric antigen receptor (CAR) or an engineered T cell receptor (TCR).The company's most advanced candidate, axicabtagene ciloleucel (axi-cel), is a CAR T therapy currently under priority review by the FDA for refractory aggressive non-Hodgkin lymphoma, including diffuse large B-cell lymphoma (DLBCL), transformed follicular lymphoma
(TFL) and primary mediastinal B-cell lymphoma (PMBCL).
This translocation is the same found in follicular lymphoma
comprises approximately 20% of all lymphomas in the United States and has a slight female predominance [1, 2].
GlobalData's clinical trial report, "Follicular Lymphoma
Global Clinical Trials Review, H1, 2016" provides an overview of Follicular Lymphoma
clinical trials scenario.
This epidemiological analysis focuses specifically on four subtypes of B-cell NHL: follicular lymphoma
, marginal zone lymphoma, diffuse large B-cell lymphoma (DLBCL), and mantle cell lymphoma.