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A discrete nodular lesion of inflammatory tissue in which granulation is significant.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Another study conducted by Gautam et al10 has also given tuberculous granuloma as the commonest type 68.9% followed by foreign body granuloma 18.9%, necrobiotic granuloma in 3.7%, suppurative granuloma 2.8% and sarcoidal granuloma in 1.9%.
Therefore, the diagnosis of a foreign body granuloma induced by honeybee sting was made.
BI-RADS 4b or above was made in 5 of 12 patients with fat necrosis, 2 of 3 patient with localized abscess, and 1 of 1 patients with foreign body granulomas.
(14) Murray et al (15) reported the case of a 66-year-old HIV-positive man who, several months after initiating HAART, experienced an exacerbation of multiple foreign body granulomas at the site of preexisting traumatic scars decades after the original injuries; however, no specific endogenous or exogenous antigen was identified.
Foreign body granuloma in the submental region due to fish bone: a case report.
INTRODUCTION: As a mass within a patient's body comprising of non-absorbable surgical material with a cotton matrix surrounded by a foreign body granuloma. (1) The incidence is found to be one in 3000 to 5000 abdominal operations.
Acute presentation generally follows a septic course with abscess formation or a pyogenic foreign body granuloma. Foreign body may remain in abscess cavity and creates multiple fistulae and intestinal obstruction.
MRI-showed blowout fracture of floor of right orbit with Minimally enhancing lesion in the region of lacrimal gland and a clinical diagnosis of foreign body granuloma or pseudotumor or chronic hematoma was made.
Foreign body granulomas after the use of dermal fillers: Pathophysiology, clinical appearance, histologic features, and treatment.
In the two monkeys that were given lower infective dose (6,000 eggs) each, there was formation of typical foreign body granulomas (Figures 4, 5, and 6) characterized by central liquefaction, surrounded by a rim of chronic inflammatory cells, comprising macrophages, plasma cells, lymphocytes, and eosinophils (Figure 7), besides large number of foreign body giant cells and fibroblasts (Figure 8).
Analysis of specimens suggested that cellulose foreign body granulomas may be a significant cause of intestinal obstruction as adhesions strangling the intestines often had cellulose-granulomas as probable initiators.
Observation of foreign body granulomas surrounding fragments of hair, had led to the suggestion that the process begins with penetration of cut hair into the skin.