freckle

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Related to freckling: Ephelides

freckle

1. a small brownish spot on the skin: a localized deposit of the pigment melanin, developed by exposure to sunlight
2. Austral slang the anus

freckle

[′frek·əl]
(medicine)
A pigmented macule resulting from focal increase in melanin, usually associated with exposure to sunlight, commonly on the face.
References in periodicals archive ?
Legius and coworkers concluded half a cohort of 40 patients with Legius syndrome confirmed by genetic analysis fulfilled the NIH diagnostic criteria for NF1 based upon the presence of the requisite number of cafe au lait spots, axillary freckling, and/or a family history compatible with NF1.