Absence of the inferior labial and lingual frenula
in Ehlers-Danlos syndrome.
Laterally, there were multiple small accessory labial frenula
Oral manifestations which may be seen include malocclusion, labiogingival adherences, gingival hypertrophy, accessory labiogingival frenula
, serrated incisal margins, dental transposition, diastema, conical teeth, enamel hypoplasia, hypodontia, and teeth erupted or exfoliated prematurely, which were present in our patient too.
In the present case, acromesomelia (relative shortening of distal and middle segments of the limbs), short stature, postaxial polydactyly of hands, hypoplastic and deformed nails and toes, and multiple frenula
of lower lip were present.
Other facial/oral manifestations are ocular hypertelorism, aplasia of alar cartilage and alopecia, hypertrophic frenula
, lingual hamartomas and ankyloglossia, dental caries, enamel hypoplasia, supernumerary and missing teeth.
Although it might also be associated with factors such as brushing trauma, abnormal frenula
attachment, dental malposition (15), or aspects like diet, i.e.
Other dental findings include neonatal teeth, serrated alveolar ridge, supernumerary frenula
and pseudo cleft lip resulting from a hyperplastic midline frenum.
* Can present as oral frenula
ulcerations with cervical adenopathy or fever.
Oral-facial-digital syndrome II (Mohr syndrome) is an autosomal recessive syndrome characterized by bilateral polysyndactylia of the halluces, bilateral hexadactylia of the hands, lobed tongue, and multiple oral frenula
and peculiar facies .
In addition, the thickness and fixation of the upper and lower labial frenula
on the alveolar ridge were adequately exposed.
On the other hand, tubulin-immunoreactive nerve networks are found throughout the subumbrellar areas containing swim musculature, including the subumbrella proper, the velarium, and the velarial frenula
. Comparison of the scyphomedusan and cubomedusan nervous systems is important since the cubomedusae were originally included within the class Scyphozoa, and only recently were elevated to class status (class Cubozoa; Werner et al., 1971, 1976).
Ankyloglossia (tongue tie): This is characterized by shortness of the lingual frenula
, which thus restricts movements of the tongue.