Tensile strength and briquettes friability
Treatment Mean maximum Standard Mean maximum tension (MPa) deviation load (kgf) T1 1.54 a 0.17 167.14 a T2 0.92 b 0.05 107.56 b T3 0.60 c 0.06 72.80 c T4 0.35 d 0.03 43.84 d T5 0.24 e 0.40 31.19 e Treatment Standard Friability
Moisture content deviation rate (%) (%d.b.) T1 17.38 3.49 13.7 T2 5.50 21.37 12.7 T3 06.09 46.17 11.9 T4 3.99 67.13 11.2 T5 4.45 69.78 10.8 * T1-100% of urban pruning; T2--50% urban pruning and 50% sugarcane bagasse; T3--25% urban pruning and 75% sugarcane bagasse; T4-10% urban pruning and 90% sugarcane bagasse; T5-100% sugarcane bagasse; Equal lowercase letters in the columns imply treatments with equivalent means, that is, that do not differ between them, at a 0.05 significance level
date Betanase 12/2012 11/2016 Daonil 03/2013 03/2015 Glamide 09/2012 08/2016 Glitisol 10/2012 10/2017 Melix 05/2011 04/2016 Table 2: Results of hardness, friability
, disintegration tests, and chemical assay of different brands of glibenclamide tablets included in the study.
This is in agreement with the study of Perfect and Kay (1994) who used air-dry aggregates and the Weibull model to estimate friability
. Munkholm and Kay (2002) also found higher values of [MATHEMATICAL EXPRESSION NOT REPRODUCIBLE IN ASCII] using aggregates with different moisture status and scaling of aggregate strength with aggregate size to estimate friability
Thus, tablets that are satisfactory in terms of hardness and friability
can be obtained.
, thickness, and diameter were also kept constant.
Therefore, MPFs structure is difficult to be damaged during the friability
measures the sand's surface brittleness and abrasion resistance on mold edges, corners, parting lines and abraded mold surfaces developed during molding, core setting and handling.
In our case surgical management with for example pneumonectomy was deemed unsuitable owing to the expected dense adhesion and pulmonary vasculature friability
after CCRT and the high risk of vascular and bronchial stump rupture even after successful surgery outweighs any potential benefits.
Ten tablets were weighed and placed into a tablet friability
tester (Model CS-1, Vanguard Pharmaceutical Machinery Inc., USA).
The mechanical and release properties of paracetamol tablets containing the extracted celluloses and two standard disintegrants- corn starch B.P and microcrystalline cellulose - were determined using crushing strength friability
disintegration time the time taken for 50% (T50) and 90% (T90) drug dissolution as assessment parameter.
* Tablets: Hardness, thickness, friability
and disintegration time.