Commercial fungal antibiotics include penicillin G, V, 0, cephalosporin, griseofulvin, fumagillin
, variotin, fusidic acid, siccanin and xanthocillin.
In a case of severe illness where substantial immunosuppression and treatment failure of albendazole monotherapy were factors, the addition of fumagillin
was effective (3).
ceranae) following the scarcity of fumagillin
in the EU.
The most common Aspergillus mycotoxins are aflatoxin, ochratoxin, patulin, and fumagillin
. The main target of these toxins is the liver.
For treatment, more than 200 compounds were tested, but only fumagillin
and several organic compounds of mercury gave acceptable results.
fumigatus produce a number of low-molecular-mass toxins, including helvolic acid, fumagillin
and gliotoxin .
fumigatus toxins, including gliotoxin, helvolic acid and fumagillin
(Takashi et al., 2004).
Treatment: Topical fumagillin
, propamidine isethionate and oral itraconazole or albendazole.
Effects of Nosema bombi and its treatment fumagillin
on bumble bee (Bombus occidentalis) colonies.
For example, TNP-470, a synthetic analog of the antiangiogenic agent fumagillin
, exhibited significant tumor regression in the Rip1-Tag2 model as a single agent ; however, its efficacy in humans was very limited, due to its short half-life and neurotoxic effects .
to get rid of any possible microsporidial or other parasitic infections .
Serological studies, have suggested that several species of Microsporidia may commonly infect immunocompetent adults; such infection is usually treated with albendazole and fumagillin