fumagillin


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fumagillin

[‚fyü·mə′jil·ən]
(microbiology)
C26H34O7 An insoluble, crystalline antibiotic produced by a strain of the fungus Aspergillus fumigatus.
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The most common Aspergillus mycotoxins are aflatoxin, ochratoxin, patulin, and fumagillin.
In 2002, oral fumagillin was established as an effective treatment for E.
fumigatus toxins, including gliotoxin, helvolic acid and fumagillin (Takashi et al.
Treatment: Topical fumagillin, propamidine isethionate and oral itraconazole or albendazole.
Effects of Nosema bombi and its treatment fumagillin on bumble bee (Bombus occidentalis) colonies.
Telomerase activity was reduced in MM cell lines in comparison with normal cells by inhibition of MetAP2 (methionine amino-peptidase) with angiostatic agents fumagillin and ovalicin.
Alan Cherrington of Vanderbilt University in Nashville, who has worked on a related drug, fumagillin, said, "Indeed, it would appear that the drug increases the breakdown of fat," though the complete mechanism is not yet known.
Endothelial alpha(v)beta3 integrin-targeted fumagillin nanoparticles inhibit angiogenesis in atherosclerosis.
En la arterioesclerosis, unidos al Fumagillin, podrian reconocer la llegada del farmaco a la placa de ateroma del endotelio mediante resonancia magnetica nuclear y disolverla.
Mersana Therapeutics has entered into a research and exclusive license agreement with Teva Pharmaceutical Industries to develop and commercialize XMT-1107, a novel fumagillin analog for the treatment of all indications, including cancer.
of spores in Fumagillin feces, aspirates topically for (bile, bronchial, keratocon-junctivitis or duodenal), and urine sediments Sarcocystis Direct No known bovihominis detection in treatment.