fumaric acid


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Related to fumaric acid: fumaric acid esters

fumaric acid

(fyo͞omăr`ĭk) or

trans-butenedioic acid,

HO2CCH=CHCO2H, unsaturated dicarboxylic acid that melts at 287°C;. Maleic acid, or cis-butenedioic acid, is a geometric isomerisomer
, in chemistry, one of two or more compounds having the same molecular formula but different structures (arrangements of atoms in the molecule). Isomerism is the occurrence of such compounds. Isomerism was first recognized by J. J. Berzelius in 1827.
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 of fumaric acid; it melts at about 140°C;. Of the two isomers fumaric acid is the more stable and can be prepared from maleic acid by heating it. Fumaric acid can be prepared by catalytic oxidation of benzene or by bacterial action on glucose. It is found in small amounts in a variety of plants and is essential to the respiration of animal and vegetable tissue. Fumaric acid is used as a substitute for tartaric acidtartaric acid,
HO2CCHOHCHOHCO2H, white crystalline dicarboxylic acid. It occurs as three distinct isomers, the dextro-, levo-, and meso- forms.
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 in beverages and baking powder. It is used as a mordant in dyeing and in the manufacture of synthetic resins and polyhydric alcohols.

fumaric acid

[fyü′mar·ik ′as·əd]
(organic chemistry)
C4H4O4 A dicarboxylic organic acid produced commercially by synthesis and fermentation; the trans isomer of maleic acid; colorless crystals, melting point 287°C; used to make resins, paints, varnishes, and inks, in foods, as a mordant, and as a chemical intermediate. Also known as boletic acid.
References in periodicals archive ?
A standard curve of each analyte (glutamic acid, citric acid, isocitric acid, [alpha]-ketoglutaric acid, malic acid, oxaloacetic acid, succinic acid, fumaric acid, and lactic acid) was produced from stock solutions (1mg/ml) in the relevant matrix (synthetic urine, 5% fatty acid-free HSA, cell culture medium acidified with 0.2% formic acid).
Dringen, "Fumaric acid diesters deprive cultured primary astrocytes rapidly of glutathione," Neurochemistry International, vol.
Types and quantities of organic acids detected in molasses hydrolysate Organic acid Concentration (mg/L) Lactic acid 3850 Malic acid 1120 Citric acid 90 Fumaric acid 20 Quinic acid Not detected Table 3.
* Preservatives: Calcium propionate, fumaric acid, phosphoric acid, potassium sorbate, sodium acid pyrophosphate, sodium propionate
Topics addressed include: sustainable biorefineries, biomass logistics, ethanol from bacteria and yeasts, isobutanol, lactic acid, fumaric acid biosynthesis and accumulation, and recent advances for microbial production of xylitol.
"We are designing a system in small jars, reducing the salt and replacing it with calcium chloride and replacing the sulfite with fumaric acid and other natural preservatives.
Different treatment modalities like cryotherapy, scarification, topical and systemic steroids, antimalarials, chlorambucil, ciclosporin, dapsone, etretinate, fumaric acid esters, isotretinoin, niacinamide, pentoxifylline, photo(chemo)therapy, potassium iodide, zileuton (a 5-lipoxygenase inhibitor), vitamin E have been tried with variable responses.
Fumaric aciduria is a rare autosomal recessive metabolic disease which is characterized with excessive fumaric acid exretion in urine.
The new formulation contains 25 mM of fumaric acid, 5 mM of benzoic acid, 70 mM of acetic acid and 342 mM of 2% sodium chloride, with a pH of 3.8.
Organic acids that have been evaluated as feed additives are malic acid, fumaric acid, and aspartic acid.
In order to enhance the biocompactibility and biodegradation, a polymer is designed from fumaric acid, 1,4-butanediol, and itaconic acid.
German biochemist Walter Schweckendieck took a dose of a related compound, fumaric acid, in 1959, believing that a deficiency of the substance was causing his psoriasis, a skin condition mediated by the immune system.