gene conversion


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

gene conversion

[′jēn kən‚vər·zhən]
(genetics)
A situation in which gametocytes of an individual that is heterozygous for a pair of alleles undergo meiosis, and the gametes produced are in a 3:1 ratio rather than the expected 2:2 ratio, implying that one allele was converted to the other.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Inherited differences in crossing over and gene conversion frequencies between wild strains of Sordaria fimicola from Evolution Canyon.
Somatic gene conversion of the rare mutation to normal cannot be excluded as DNA from peripheral blood was tested and the DNA from the parent with the non-founder mutation was not sequenced.
It is suggested that a number of events including gene conversion have occurred during evolution which has altered the clusters of [beta]-globin gene in specific ways in different eutherian (mammalian) orders.
The same mechanism used for gene conversion on the Y can result in nonreciprocal recombination between two arms of the palindromes (Lange et al., 2009).
There are many factors that influence haplotype structure, including the mutation, gene conversion, and recombination rates.
Phylogeny and sequence change link different genes in the same genome as surely as they link orthologous genes in different genomes, with the extra complexities of transposition, gene conversion and unequal recombination all playing their part.
Mozaic gene conversion after a tandem duplication of mtDNA sequence in Diomedeidae (albatrosses).
(2001) also reported higher incidences of crossing over and gene conversion were in the strains isolated from SFS than strains from the NFS.
But a process known as "gene conversion," in which similar genes can acquire mutations from one another during cell division, complicates tracking the exact history of the mutation's spread.
This pattern of relationship and the lack of evidence of gene conversion from horizontal gene transfer at this locus, demonstrates that, as for the Lyme borreliosis spirochetes (10), the intergenic spacer region is both sensitive and sufficient for genotyping the relapsing fever group of Borrelia species.
The mating type of the yeast is entirely determined by the expressed copy at MAT, but a cell can switch its mating type by replacing (via gene conversion) the current sequence at MAT with the sequence of the other type contributed from HML or HMR.