Changes in gene expression
underlie many biological phenomena.
Rosetta Inpharmatics' technology generates coherent gene expression
data from DNA chips or microarrays, and applies powerful genomic analysis tools to provide comprehensive, simultaneous information about all relevant genes and targets within a cell.
"NetGenics Gene Expression
DataMart frees scientists to focus on science versus data integrity."
Automated gene expression
profiling is complemented by recent advances in gene mapping (see the article in this issue by Grisel, pp.
In a paper published on 3rd June in Science, researchers at the Centre for Genomic Regulation (CRG) led by senior group leader Miguel Beato in collaboration with the University Pompeu Fabra, the Institute for Biomedical Research in Barcelona, and the University Rovira i Virgili in Tarragona, Spain, have described for the first time a new pathway generating energy within the cell nucleus for remodelling chromatin and reprogramming gene expression
. They have also identified the function of enzymes involved at every step of this process and how they are activated in response to stress signals.
Exploring gene expression
and epigenetics, contributors from a wide range of medical specialties look first at eukaryotic DNA methylation, then at how to integrate genomic medicine into clinical practice.
In some 144 patients, a gene expression
biomarker was identified that demonstrated an agreement of 69% with brain amyloid PET imaging.
Based on the gene expression
profiles, the selection of gene with the recognition of the optimal subset of relevant genes is one of the foremost challenges in cancer classification.
In addition, the US Patent and Trademark Office's US Patent covers UC's techniques that enable sequence-specific repression or activation of gene expression
in all types of cells, including both prokaryotic and eukaryotic cells.
The first step in gene expression
is the binding to DNA of an enzyme called RNA polymerase.
Summary: TEHRAN (FNA)- Gene expression
in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases.
The researchers conducted a gene expression
analysis of colorectal, prostate cancer and glioblastoma cell lines and patient derived tissues that were both treated with ONC201.