Genome uses gene scanning
to detect changes in the genes, chromosomes and proteins that can lead to genetic diseases, allowing researchers to prevent and eradicate chronic diseases and cancer.
Although, investigators have applied different methods (Gene Scanning
and Heteroduplex gel electrophoresis) to detect rearrangements, both approaches have similar sensitivities in clonality PCR assays .
and genotyping with snapback primers requires only 2 primers, symmetric PCR with a saturation dye, and high-resolution melting.
The more useful information that gene scanning
can provide today is how we will likely react to various pharmaceuticals.
With support from the National Institutes of Health, researchers found those mutations through whole exome sequencing -- a new gene scanning
technology that cuts the cost and time of searching for rare mutations.
Duncan Odom, project researcher adds, "We developed an efficient gene scanning
technology so we could map genome binding sites for many transcription factors in a human organ.
'Genome' uses gene scanning
to detect changes in the genes, chromosomes, and proteins that can lead to genetic diseases, allowing researchers to prevent and eradicate chronic diseases and cancer.
A successful experiment depends on primer design (gene scanning
) and probe design (genotyping), as well as on DNA quantity and quality.
As the new gene scanning
software module was only recently made available on the LightCycler 480, we were able to find data from only one other study (9) comparing the results of both instruments for factor VIII mutations.
Recently, high-resolution melting analysis was introduced as a simple, closed-tube, gene scanning