Genome uses
gene scanning to detect changes in the genes, chromosomes and proteins that can lead to genetic diseases, allowing researchers to prevent and eradicate chronic diseases and cancer.
Although, investigators have applied different methods (
Gene Scanning and Heteroduplex gel electrophoresis) to detect rearrangements, both approaches have similar sensitivities in clonality PCR assays [14].
Gene scanning and genotyping with snapback primers requires only 2 primers, symmetric PCR with a saturation dye, and high-resolution melting.
The more useful information that
gene scanning can provide today is how we will likely react to various pharmaceuticals.
With support from the National Institutes of Health, researchers found those mutations through whole exome sequencing -- a new
gene scanning technology that cuts the cost and time of searching for rare mutations.
Duncan Odom, project researcher adds, "We developed an efficient
gene scanning technology so we could map genome binding sites for many transcription factors in a human organ.
'Genome' uses
gene scanning to detect changes in the genes, chromosomes, and proteins that can lead to genetic diseases, allowing researchers to prevent and eradicate chronic diseases and cancer.
A successful experiment depends on primer design (
gene scanning) and probe design (genotyping), as well as on DNA quantity and quality.
As the new
gene scanning software module was only recently made available on the LightCycler 480, we were able to find data from only one other study (9) comparing the results of both instruments for factor VIII mutations.
Recently, high-resolution melting analysis was introduced as a simple, closed-tube,
gene scanning technique (13).