Desirable genetic markers
should meet the following criteria: 1) high level of genetic polymorphism; 2) co-dominance (so that heterozygotes can be distinguished from homozygotes); 3) clear distinct allele features (so that different alleles can be identified easily); 4) even distribution on the entire genome; 5) neutral selection (without pleiotropic effect); 6) easy detection (so that the whole process can be automated); 7) low cost of marker development and genotyping (Inexpensive to develop and apply); 8) high reproducibility (High robust and repeatable across different tissue types and different laboratories); and 9) unaffected by environmental and developmental variation .
Understanding towards genetic diversity and population structure of malaria parasites are the crucial steps to make an effective anti-malarial control measure, and for such studies identification of high diversity resolving genetic markers
are equally essential.
Up to 10 seeds of this genetic marker
stock may be obtained upon written request and agreement to return increased seed to the corresponding author.
One of the most exciting areas of scientific research today is the identification of the genetic markers
of disease through the collection and analysis of an individual's DNA.
In the study, white women with the genetic marker
were nearly 70 percent more likely to have breast cancercompared to those without the marker.
"By using genetic markers
to blood and lung samples, we have discovered that there are certain indicators that signal increased susceptibility to this influenza.
Six out of 10 women without other genetic markers
of ovarian cancer risk had the KRAS variant.
Genomewide association studies have identified well over a dozen genetic markers
that are associated with prostate cancer risk.
Thus, in 2008 the internist was suddenly confronted with GWAS articles and reports in major clinical journals as dozens of genes or genetic markers
were linked to nearly 40 common diseases.
"During the past seven years we have been investigating ways to identify soybean cyst nematode resistant traits in soybeans using genetic markers
. By sharing what we know, researchers around the world will be able to more accurately identify resistant soybeans and breed for them," said Bob Reiter, Vice President of Breeding Technology for Monsanto.
A genetic marker
on chromosome 11, for example, explains only 15 percent of asthma sufferers, and other candidate genes for asthma are being examined on chromosome 5, 6, 13, and 14.
The most important genetic marker
found in the study has also been found to be close to one implicated in schizophrenia.