Reis, "Projections to the subcortical forebrain from anatomically defined regions of the medial geniculate body
in the rat," The Journal of Comparative Neurology, vol.
The researchers showed that dyslexic adults have a malfunction in a structure that transfers auditory information from the ear to the cortex is a major cause of the impairment: the medial geniculate body
in the auditory thalamus does not process speech sounds correctly.
When affected individuals performed tasks that required the recognition of speech sounds, as compared to recognize the voices that pronounced the same speech, magnetic resonance tomography (MRT) recordings showed abnormal responses in the area around the medial geniculate body
. In contrast, no differences were apparent between controls and dyslexic participants if the tasks involved only listening to the speech sounds without having to perform a specific task.
Since efavirenz crosses the BBB, it is relevant to investigate its histochemical effect on the superior colliculi and lateral geniculate body
. It is probable that the adverse effects of efavirenz on dizziness and headache may be due to direct effect of efavirenz on the superior colliculus and lateral geniculate body
[24,25] Neuronal loss has also been reported in the cochlear nucleus, inferior colliculus, medial geniculate body
, and the temporal lobe.
[sup], Increasingly converging evidence suggests the thalamic nuclei (the thalamus pulvinar, and the dorsal and medial divisions of the medial geniculate body
) have anatomical connections to structures of different sensory modalities and/or corresponding neurons to integrate multisensory information, sometimes even before the information has reached the neocortical areas.
The next stage of the pathway is the lateral geniculate nucleus (LGN), sometimes termed the lateral geniculate body
(LGB) or lateral geniculate complex (LGC).
Out of 15 patients, traumatic optic neuropathy was present in 4(26.7%) patients, secondary optic atrophy in 3(20%) patients, macular edema in 3(20%) patients, posterior visual pathway lesion (lateral geniculate body
1<6.7%>patients, occipital cortex 1<6.7%> patients) in 2 patients & vitreous hemorrhage in 3(20.0%) patients.
Histological studies of the effects of monosodium glutamate on the medial geniculate body
of adult Wistar rats.
Laboratory and clinical evidence now suggest the following wave origins: (1) auditory nerve; (2) cochlear nucleus; (3) superior olivary complex; (4) midbrain, possibly nucleus of the lateral lemniscus; (5) inferior colliculus; (6) medial geniculate body
; and (7) possibly auditory radiation from the thalamus to temporal cortex.