genomic imprinting


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genomic imprinting

[jə¦nō·mik im‚print·iŋ]
(genetics)
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BWS is a genomic imprinting disorder characterized by abdominal wall defects, macroglossia, pre- and postnatal overgrowth, neonatal hypoglycemia, visceromegaly, and increased risk of developing cancer in childhood, such as Wilms' cancer, hepatoblastoma, neuroblastoma, adrenocortical carcinoma, and rhabdomyosarcoma.
Mammalian-specific genomic functions: Newly acquired traits generated by genomic imprinting and LTR retrotransposon-derived genes in mammals .
Lack of MTHFR activity due to presence of its polymorphic variants will reduce the availability of methyl group donors that are needed for methylalation of DNA (9) which may adversely affect the global genome methylation and also the genomic imprinting of paternal genes in spermatogenetic cells.
Genomic imprinting occurs when epigenetic marks are established in the germ line such that sperm or eggs carry information that transfers to the next generation.
Results: Vitrifications of mature oocytes and embryos obtained better clinical outcomes and did not increase the risks of DNA damage, spindle configuration, embryonic aneuploidy, and genomic imprinting as compared with fresh and slow-freezing procedures, respectively.
Genomic imprinting refers to differential expression of a locus between the maternally and paternally inherited alleles.
There is only limited evidence of genomic imprinting in oviparous species, such as fish [10].
Family history has been observed in 10% of moyamoya patients (9) and familial moyamoya disease may be autosomal dominant with incomplete penetrance that depends on age and genomic imprinting factors (10).
Previous studies have shown that DNA methylation can affect gene regulation, phenotypic trait, genomic imprinting, and disease development (Li et al.
Different aspects of heredity are examined in several papers, including radiation effects, analysis of genomic data to detect natural selection, genomic imprinting in plants, the origins of animal cells, meiotic recombination, and evolution of sex pheremones.
Genomic imprinting is an epigenetic process involved in the control of gene expression in a parent-of-origin-specific manner (1).
reports that genomic imprinting, a process that specifically shuts down one of the two gene copies found in each mammalian cell, prevents the reservists from being called up prematurely.