(10,12) The importance of making the distinction among maturation delay, pre-GCNIS, and GCNIS is related to the high rate of progression of GCNIS to an invasive germ cell
tumor (perhaps approaching 100% if the follow-up period is sufficiently lengthy) (6) but the absence of information regarding the progression of both maturation delay and pre-GCNIS to an invasive tumor.
Ainul Mardhiah Ahmad Safiuddin is suffering from Germ Cell
Tumour - a rare type of cancer
Ovarian tumours were broadly classified into five major types in accordance with the World Health Organisation (WHO) system for Ovarian Neoplasms; 8 surface epithelialstromal tumours, germ cell
tumours, sex cord-stromal tumours, metastatic tumours, and miscellaneous tumours.
Mouse germ cell
clusters form by aggregation as well as clonal divisions.
Both seminoma and nonseminoma tumors are believed to be derived from carcinoma in situ (CIS), also known as intratubular germ cell
neoplasia (ITGCN), where the generation and expansion of tumor cells is restricted in the seminiferous tubules.
This phenomenon, however cannot conclusively comply with several genes in stem cells and germ cells
, of which H3K4me3 regions are presented without transcription.
Mazumdar et al., "Paclitaxel, ifosfamide, and cisplatin second-line therapy for patients with relapsed testicular germ cell
cancer," Journal of Clinical Oncology, vol.
Goldman, "Pediatric central nervous system germ cell
tumors: a review," Oncologist, vol.
Coney, "Intracranial germ cell
tumors," The Oncologist, vol.
 "International Germ Cell
Consensus Classification: a prognostic factor-based staging system for metastatic germ cell
Appropriate culture system is a critical and essential step for successful differentiation of male germ cells
. Co-culture with Sustentacular cells, gonadal stromal cells, Vero cells and enriched medium with Retinoic acid and testicular extraction are investigated as culture systems that can increase expression of male germ cell
markers (Drusenheimer et al., 2006; Nayernia et al, 2006; Park et al, 2009; Zanganeh, Rastegar et al., 2013; Hou et al.).
An ovarian teratoma develops from a totipotential germ cell
(a primary oocyte) that is retained within the ovary.