germ cell


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Related to germ cell: Germ cell tumor

germ cell

a sexual reproductive cell; gamete

germ cell

[′jərm ‚sel]
(biology)
References in periodicals archive ?
An ovarian teratoma develops from a totipotential germ cell (a primary oocyte) that is retained within the ovary.
The use of immunohistochemical stains is imperative in the diagnosis of germ cell tumours.
Researchers presented the results of a phase 2 trial of paclitaxel (T) plus ifosfamide (I) followed by high-dose carboplatin (C) plus etoposide (E) with stem-cell support (TICE) among 101 patients with relapsed advanced germ cell tumours (GCTs-71 with testicular tumours).
The significance of spermatic cord LVI in the absence of cord soft tissue invasion has not been evaluated, to our knowledge, in testicular germ cell tumors.
Risk factors for testicular cancer include cryptorchidism (testicular maldescent), carcinoma in situ (intratubular germ cell neoplasia), history of testicular cancer or extragonadal germ cell tumor, family history, HIV infection, Down syndrome, and testicular trauma.
Considering the partly similar reaction of niche cells in response to either in vitro removal of SSCs using differential plating or in vivo elimination of SSCs using busulfan treatment (19,22), it could be suggested that removal of SSCs presented in the current research could serve as a model to study the events ensuing testicular germ cell damage and the mechanisms involved in regeneration of testicular germ cells afterwards.
Management of malignant germ cell neoplasms generally includes fertility-sparing surgery--with or without neoadjuvant combination bleomycin, etoposide, and cisplatin (BEP)--and is typically associated with a favorable prognosis (Cancer Treat Rev.
In contrast to the slow-growing epithelial ovarian tumors, germ cell malignancies grow rapidly and are characterized by subacute pelvic pain related to capsular distention (2), hemorrhage or necrosis.
A major cause of male infertility is the failure of precursor germ cells in the testes to undergo a type of cell division called meiosis to form functional sperm cells.
Teratomas are germ cell tumors and they are uncommon neoplasms that arise in the gonads; the mediastinum is the second most common extragonadal site of these tumors [3,4].
His serum germ cell tumor markers (lactate dehydrogenase, [beta]-human chronic gonadotropin, and a-fetoprotein) were in normal range.