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The condition of having an abnormally small number of platelets in the circulating blood.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a decrease in the number of platelets to fewer than 200,000 per mm3 in the peripheral blood. It may result from the redistribution of platelets in the bloodstream or from hemorrhage. Other causes are the intensified loss of platelets associated with thrombocytopenic purpura, splenomegaly, disseminated intravascular thrombosis, and the use of certain drugs. Thrombocytopenia may also result from disturbance of platelet formation in the bone marrow in leukemia or aplastic anemia, and from ionizing radiation. Blood clotting is impaired in thrombocytopenia, resulting in a tendency of the mucous membranes to bleed, as well as in hemorrhaging and the appearance of petechiae in the internal organs. Bleeding usually becomes continuous when the platelet count falls below 20,000–30,000 per mm3 of blood. Therapy involves treatment of the underlying disease, administration of hemostatics, and transfusion of platelets.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
OF PATIENTS <100 X [10.sup.9]/L 04 <70 X [10.sup.9]/L 22 <40 X [10.sup.9]/L 04 RESULTS: In our study incidence of gestational thrombocytopenia were 14 out of 30 patients amounting to 46% incidence.
Gestational Thrombocytopenia is a clinical condition that occurs most commonly during late pregnancy and has a benign course.
Gestational thrombocytopenia. A plea for conservative management.
9 Some studies have demonstrated slight but statistically insignificant fall in mean platelet count within normal range, which reflects development of the gestational thrombocytopenia. (10)
Present study constitutes incidence of gestational thrombocytopenia about 14%.
Thrombocytopenia in pregnancy is an incidental finding, it can occur in normal pregnancies as gestational thrombocytopenia and pregnancies associated with complications like HDP, HELLP syndrome.