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Astrocytes do not express AQP1 in normal conditions, but in a recent report (13) in a nonhuman primate (Macaca fascicularis), a subtype of astrocytes mainly located in the white matter and the glia limitans did express this protein in the processes and perivascular endfeet.
Bergman glia constitutes a large volume fraction in cerebellum (33%), more than three times that of hippocampus and cortex [29, 40, 41].
We showed that fluorocitrate, which specifically blocks glial metabolic activity by inhibiting the activity of aconitase, a Krebs cycle enzyme found exclusively in glia [33-36] and served as positive control in this study, reduced the pain response in both models as previous reported [12, 37, 38].
* Microglia: These glia constitute the brain's immune defense, operating behind the blood-brain barrier to identify, hunt down, and destroy organisms that invade the brain.
Similar effects were obtained when the concentration of [K.sup.+] ions in the axon perfusate was drastically reduced, thereby inducing depolarization of the axon but not of the glia. These results suggested that the increased rate of synthesis, delivery, or both, of [[H.sup.3]]RNA to the axon perfusate was mediated by the release of one or more neurotransmitters from the depolarized axon that activated receptors in the glial plasma membrane.
Alcohol is thought to affect the migration of neuronal and glia cells in the foetus's developing brain.
Mark Saltzman and Melissa Mahoney of Cornell University in Ithaca, New York first enzymatically dissociated fetal rat brain cells, resulting in a mixture of differentiated cells resembling neurons and glia. In a separate step, they produced microparticles from lactide-co-glycolide, in which nerve growth factor (NGF) and agents to alter its release were encapsulated.
Tests revealed that the mice who could not chew had lost essential cells called glia in the hippocampus, the area of the brain critical for learning.
(HAP607) THOMAS OESTERLING, CEO of GLIATECH INC (GLIA), describes the company's business and its background; prospects for the industry, with positive and negative trends; competitive threats; strategic opportunities for the firm including its marketing plans and acquisition potential; management strength and organization; and the financial prospects of the firm looking forward.
These helper cells, called olfactory ensheathing glia (EG), are found only in nerves that carry odor sensations to the brain.
Once early-stage motor neurons and glia diverged, they have very different properties.
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