"The activation of glial cells
we observed in our studies releases inflammatory mediators that are thought to sensitize pain pathways and contribute to symptoms such as fatigue," says Dr.
Freeman, "Analysis of glial cell
development and function in Drosophila," Cold Spring Harbor Protocols, vol.
It has been found that inflammatory actions may be involved in the process of progressive degeneration of DA neurons in PD.[sup] HE staining showed that there was no significant difference in the number of glial cells
in Groups A, PX, GDX, and PX + GDX, indicating that PX or GDX did not lead to an obvious glial cell
activation is associated with NOS-2 (iNOS) and NOX-2 induction [22-24] in brain injury.
The common evolutionary origin of neural supportive cells remains uncertain, but independent specialization of the glial cells
from two or more stem animal groups has been proposed, since glia appears to be lacking in the basal species of many major animal phyla (Hartline, 2011).
were cultured at 37[degrees]C and 5 % C[O.sub.2] in 24 well tissue culture plates under sterile conditions, medium was changed every third day.
Previous studies believed that glial cells
play an important role in information processing in the brain and the formed neural network connection together with neurons, and are closely related to neurotransmitter synthesis, uptake, neurotrophy, repair and other functions, may be unique targets for novel strategies in the treatment of major depression.
In conclusion, we have identified a PAR1 axis of glial cell
activation triggered by plasmin or the plasminogen system.
Secondly, potassium homeostasis regulates glial cell
New discoveries have added to a lengthening list of what experts now know about the critical functions of glia, the most recent being the revelation that glial cells
may be responsible for a hitherto unknown system designed to remove debris and toxic waste products from the brain.
They address studying the neural development of the fly, recording and imaging, and studying its behavior, and molecular, genetic, electrophysiological, optical imaging, behavioral, and developmental methods to examine cell-fate specification, cell morphogenesis, neural connectivity, neuronal and glial cell
processes, and strategies to mark and manipulate cells.
Transfection experiments with the promoter-luciferase reporter in different cell contexts showed that, similar to the in vivo situation, full [E.sub.2] up-regulation of the Aro-B gene is restricted to glial cell
lines, such as the human glial cell
line U251-MG (Menuet et al.