Nonsuppurative myelitis is oriented on the ventral horn involving neuronal degeneration with satellitosis (black arrow), neuronophagia (arrowhead), and glial nodule formation (blue arrow), accompanied by perivascular mononuclear cell I accumulation and gliosis
. Scale bar indicates 60 pm.
In all cases, they were apparently empty, with mild axonal degeneration and multifocal gliosis
. There were no changes in the neuronal bodies.
[4-6] Excess deposition of iron causes neuronal degeneration, gliosis
, and spheroid formation (Vacuolization).
In most cases there was no hyperintense gliosis
area around cavernous malformations in FLAIR images; narrow marginal gliosis
was observed only in 16.3% of patients.
This tendency of two peaks is consistent with a previous finding. Reactive gliosis
and neuronal swelling also have been observed in the hippocampus of rats subjected to blast injury. Overall, neuronal injury and gliosis
in frontal lobe and hippocampus were significantly higher at 3 days post-bTBI induced by moderate blast.
There is also increased signal indicating gliosis
and/or dysplasia seen posterolateral to the mass with a single focus of cystic change and no evidence of communication with the ventricular system in the axial plane.
Morphologic diagnoses of the cerebellum included multifocal, subacute Purkinje cell degeneration, necrosis, with Bergmann's astrocytosis, granular cell atrophy, and chronic, locally extensive encephalomalacia with mineralization, gliosis
, spongiosis, neovascularization, and gitter cell infiltration.
demonstrated in seven patients being 3.18% of the population.
Vitrectomy was performed at two months, after which cystic gliosis
and optic nerve avulsion were detected.
On the other hand, gliosis
may hinder regeneration as the mechanical barrier of the gliotic scar is generally considered impenetrable for axons (6-9,19,20).
At a biochemical and molecular level, ASH ameliorated the HFD-induced reactive gliosis
and microgliosis and suppressed the expression of inflammatory markers such as RRARy, iNOS, MCP1, TNF[alpha], IL-1[beta] B and IL-6.