glomerulonephritis


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Related to glomerulonephritis: nephrotic syndrome, acute glomerulonephritis

nephritis

nephritis (nəfrīˈtəs), inflammation of the kidney. The earliest finding is within the renal capillaries (glomeruli); interstitial edema is typically followed by interstitial infiltration of lymphocytes, plasma cells, eosinophils, and a small number of polymorphonuclear leukocytes. The disease is thought to be immunological, but immunoglobulins and drug antigens have been found in only a few cases. The damage is usually reversible when the cause is recognized and removed, but severe cases can progress to fibrosis and renal failure. The disease can take several forms. Pyelonephritis is usually associated with a bacterial infection transmitted from the bladder or blood; it affects the renal pelvis and is treated with antibiotics. Glomerulonephritis, or Bright's disease, causes degenerative changes in the glomeruli and is believed to be an allergic response to infection elsewhere in the body. Symptoms include headache, mild fever, puffiness of the eyes and face, high blood pressure, and discoloration of the urine. Treatment includes bed rest and limiting the intake of water, sodium, and proteins, and, if necessary, dialysis; antibiotics are given to halt infections (e.g., streptococcal) invasion. The disease occurs more frequently among the young. About 95% of patients recover from the acute phase of the disease; however, if glomerulonephritis becomes chronic, renal damage results after many years, causing kidney failure.
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glomerulonephritis

[glə¦mər·yə·lō·nə¦frīd·əs]
(medicine)
Inflammation of the kidney, primarily involving the glomeruli.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
[41.] Briganti EM, Dowling J, Finlay M, et al The incidence of biopsy-proven glomerulonephritis in Australia.
All patients were found to have crescentic glomerulonephritis (GN).
The common clinical situations where biopsy is needed are Nephrotic Syndrome (NS), prolonged Acute Renal Failure, Rapidly Progressive Renal Failure (RPRF), non-nephrotic proteinuria, isolated microscopic haematuria, chronic glomerulonephritis, unexplained Chronic Renal Failure (CRF) with normal kidney size and familial renal disease.
Detection rate of the main secondary glomerulonephritis in China
The association of ANCA with glomerulonephritis was first described in 1991; in this report, nine patients with hydralazine-induced glomerulonephritis were found to have antibodies to myeloperoxidase and elastase (8).
Chin et al., "Global evolutionary trend of the prevalence of primary glomerulonephritis over the past three decades," Nephron Clinical Practice, vol.
Nachman, "ANCA glomerulonephritis and vasculitis," Clinical Journal of the American Society of Nephrology, vol.
indicated that corticosteroids were necessary to treat pulmonary hemorrhage with poststreptococcal glomerulonephritis in an adult [20].
There have been some reported cases of glomerulonephritis characterized by monoclonal IgA glomerular deposits [7-12].
van Paassen et al., "Improved outcome in anti-neutrophil cytoplasmic antibody (ANCA)associated glomerulonephritis: a 30-year follow-up study," Nephrology Dialysis Transplantation, vol.